Tumoral markers in tumors of the pineal region

被引:6
作者
Faure-Conter, C. [1 ]
机构
[1] Ctr Leon Berard, F-69008 Lyon, France
关键词
Tumoral markers; Pineal tumor; Germ cell tumor; HUMAN CHORIONIC-GONADOTROPIN; ALPHA-FETOPROTEIN; CEREBROSPINAL-FLUID; CHEMOTHERAPY; SERUM; RECOMMENDATIONS; RADIATION; STANDARDS; CHILDREN; OPTIONS;
D O I
10.1016/j.neuchi.2013.12.006
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In cases of pineal tumors, a germ cell tumor should always be suspected. As some of them are secreting tumors, tumoral markers (AFP and/or hGC) are an important part of the diagnostic process. Their positivity either in the serum and/or in the cerebrospinal fluid may lead to an accurate diagnosis, avoiding a potentially dangerous surgical biopsy. Follow-up of tumoral markers is useful during and after treatment in order to monitor response to chemotherapy or a remission status. (C) 2014 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:143 / 145
页数:3
相关论文
共 20 条
[1]   Pattern of relapse and outcome of non-metastatic germinoma patients treated with chemotherapy and limited field radiation: the SFOP experience [J].
Alapetite, Claire ;
Brisse, Herve ;
Patte, Catherine ;
Raquin, Marie Anne ;
Gaboriaud, Genevieve ;
Carrie, Christian ;
Habrand, Jean Louis ;
Thiesse, Philippe ;
Cuilliere, Jean Claude ;
Bernier, Valerie ;
Ben-Hassel, M. ;
Frappaz, Didier ;
Baranzelli, Marie Christine ;
Bouffet, Eric .
NEURO-ONCOLOGY, 2010, 12 (12) :1318-+
[2]   ALPHAFETOPROTEIN AND HUMAN CHORIONIC-GONADOTROPIN DETERMINATION IN CEREBROSPINAL-FLUID - AID TO THE DIAGNOSIS AND MANAGEMENT OF INTRACRANIAL GERM-CELL TUMORS [J].
ALLEN, JC ;
NISSELBAUM, J ;
EPSTEIN, F ;
ROSEN, G ;
SCHWARTZ, MK .
JOURNAL OF NEUROSURGERY, 1979, 51 (03) :368-374
[3]   Diagnostic sensitivity of serum and lumbar CSF bHCG in newly diagnosed CNS germinoma [J].
Allen, Jeffrey ;
Chacko, Jeena ;
Donahue, Bernadine ;
Dhall, Girish ;
Kretschmar, Cynthia ;
Jakacki, Regina ;
Holmes, Emi ;
Pollack, Ian .
PEDIATRIC BLOOD & CANCER, 2012, 59 (07) :1180-1182
[4]  
[Anonymous], 1997, J Clin Oncol, V15, P594
[5]   Prognostic factors in children with localized malignant nonseminomatous germ cell tumors [J].
Baranzelli, MC ;
Kramar, A ;
Bouffet, E ;
Quintana, E ;
Rubie, H ;
Edan, C ;
Patte, C .
JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (04) :1212-1218
[6]  
Basuyau JP, 2000, B CANCER, V87, P723
[7]   Combined treatment modality for intracranial germinomas: results of a multicentre SFOP experience [J].
Bouffet, E ;
Baranzelli, MC ;
Patte, C ;
Portas, M ;
Edan, C ;
Chastagner, P ;
Mechinaud-Lacroix, F ;
Kalifa, C .
BRITISH JOURNAL OF CANCER, 1999, 79 (7-8) :1199-1204
[8]   Establishment, value assignment, and characterization of new WHO reference reagents for six molecular forms of human chorionic gonadotropin [J].
Bristow, A ;
Berger, P ;
Bidart, JM ;
Birken, S ;
Norman, RJ ;
Stenman, UH ;
Sturgeon, C .
CLINICAL CHEMISTRY, 2005, 51 (01) :177-182
[9]  
Eche N, 2001, B CANCER, V88, P1177
[10]   Early predicted time to normalization of tumor markers predicts outcome in poor-prognosis nonseminomatous germ cell tumors [J].
Fizazi, K ;
Culine, S ;
Kramar, A ;
Amato, RJ ;
Bouzy, J ;
Chen, I ;
Droz, JP ;
Logothetis, CJ .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (19) :3868-3876