Reliability of MR Quantification of Rotator Cuff Muscle Fatty Degeneration Using a 2-point Dixon Technique in Comparison with the Goutallier Classification: Validation Study by Multiple Readers

被引:35
作者
Horiuchi, Saya [1 ]
Nozaki, Taiki [1 ,2 ]
Tasaki, Atsushi [3 ]
Yamakawa, Akira [4 ]
Kaneko, Yasuhito [2 ,5 ]
Hara, Takeshi [6 ]
Yoshioka, Hiroshi [2 ]
机构
[1] St Lukes Int Hosp, Dept Radiol, Chuo Ku, 9-1 Akashi Cho, Tokyo 1048560, Japan
[2] Univ Calif Irvine, Dept Radiol Sci, Irvine, CA 92717 USA
[3] St Lukes Int Hosp, Dept Orthopaed Surg, Tokyo, Japan
[4] Univ Tokyo, Grad Sch Med, Div Clin Biotechnol, Tokyo, Japan
[5] Saitama Municipal Hosp, Dept Orthopaed Surg, Saitama, Japan
[6] Gifu Univ, Grad Sch Med, Div Regenerat & Adv Med Sci, Dept Intelligent Image Informat, Gifu, Japan
关键词
2-point Dixon MR quantification; fatty degeneration; reproducibility; Goutallier classification; imaging biomarker; TEARS; REPAIR; SUPRASPINATUS; INFILTRATION; AGREEMENT; ATROPHY;
D O I
10.1016/j.acra.2017.03.026
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Rationale and Objectives: Presurgical assessment of fatty degeneration is important in the management of patients with rotator cuff tears. The Goutallier classification is widely accepted as a qualitative scoring system, although it is highly observer-dependent and has poor reproducibility. The objective of this study was to quantify fatty degeneration of the supraspinatus muscle using a 2-point Dixon technique in patients with rotator cuff tears by multiple readers, and to evaluate the reproducibility compared to Goutallier classification. Materials and Methods: Two hundred patients with rotator cuff tears who underwent magnetic resonance imaging (MRI), including 2-point Dixon sequence at 3.0-T, were selected retrospectively, Qualitative and quantitative analyses of fatty degeneration were performed by two radiologists and three orthopedic surgeons independently. The fat quantification was performed by measuring signal intensity values of in phase (S(In)) and fat image (S(Fat)), and calculating fat fraction as S(Fat)/S(In). The reproducibility of MR quantification was analyzed by the intra- and interclass correlation coefficients and Bland-Altman plots. Results: The interobserver agreement of the Goutallier classification among five readers was moderate (k = 0.51), whereas the interclass correlation coefficient regarding fat fraction value quantified in 2-point Dixon sequence was excellent (0.893). The mean differences in fat fraction values from the individual segmentation results were from -0.072 to 0.081. Proposed fat fraction grading and Goutallier grading showed similar frequency and distribution in severity of rotator cuff tears. Conclusions: Fat quantification in the rotator cuff muscles using a 2-point Dixon technique at 3.0-T MRI is highly reproducible and clinically feasible in comparison to the qualitative evaluation using Goutallier classification.
引用
收藏
页码:1343 / 1351
页数:9
相关论文
共 21 条
[1]   The relationship between tear severity, fatty infiltration, and muscle atrophy in the supraspinatus [J].
Barry, Jeffrey J. ;
Lansdown, Drew A. ;
Cheung, Sunny ;
Feeley, Brian T. ;
Benjamin, C. .
JOURNAL OF SHOULDER AND ELBOW SURGERY, 2013, 22 (01) :18-25
[2]  
Bland JM, 1999, STAT METHODS MED RES, V8, P135, DOI 10.1177/096228029900800204
[3]   STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT [J].
BLAND, JM ;
ALTMAN, DG .
LANCET, 1986, 1 (8476) :307-310
[4]   Arthroscopic repair of massive rotator cuff tears with stage 3 and 4 fatty degeneration [J].
Burkhart, Stephen S. ;
Barth, Johannes R. H. ;
Richards, David P. ;
Zlatkin, Michael B. ;
Larsen, Mitchell .
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, 2007, 23 (04) :347-354
[5]  
COFIELD RH, 1982, SURG GYNECOL OBSTET, V154, P667
[6]   A POWER PRIMER [J].
COHEN, J .
PSYCHOLOGICAL BULLETIN, 1992, 112 (01) :155-159
[7]   Fatty degeneration of the muscles of the rotator cuff: Assessment by computed tomography versus magnetic resonance imaging [J].
Fuchs, B ;
Weishaupt, D ;
Zanetti, M ;
Hodler, J ;
Gerber, C .
JOURNAL OF SHOULDER AND ELBOW SURGERY, 1999, 8 (06) :599-605
[8]   Fatty infiltration and atrophy of the rotator cuff do not improve after rotator cuff repair and correlate with poor functional outcome [J].
Gladstone, James N. ;
Bishop, Julie Y. ;
Lo, Ian K. Y. ;
Flatow, Evan L. .
AMERICAN JOURNAL OF SPORTS MEDICINE, 2007, 35 (05) :719-728
[9]   Using chemical-shift MR imaging to quantify fatty degeneration within supraspinatus muscle due to supraspinatus tendon injuries [J].
Gokalp, Gokhan ;
Yildirim, Nalan ;
Yazici, Zeynep ;
Ercan, Ilker .
SKELETAL RADIOLOGY, 2010, 39 (12) :1211-1217
[10]  
GOUTALLIER D, 1994, CLIN ORTHOP RELAT R, P78