Biologic Therapies in HIV-infected Patients with Psoriasis: An Italian Experience

被引:44
作者
Bardazzi, Federico [1 ]
Magnano, Michela [1 ]
Campanati, Anna [2 ]
Loconsole, Francesco [3 ]
Carpentieri, Antonio [3 ]
Potenza, Concetta [4 ]
Bernardini, Nicoletta [4 ]
Di Lernia, Vito [5 ]
Carrera, Carlo [6 ]
Raone, Beatrice [1 ]
Patrizi, Annalisa [1 ]
Loi, Camilla [1 ]
机构
[1] Univ Bologna, Div Dermatol, Dept Specialized Clin & Expt Med, Via Massarenti 1, IT-40138 Bologna, Italy
[2] Polytech Marche Univ, United Hosp Ancona, Dermatol Unit, Dept Clin & Mol Sci, Ancona, Italy
[3] Policlin Bari, Clin Dermatol, Bari, Italy
[4] Univ Rome La Sapienza Polo Pontino, Dept Dermatol, Rome, Italy
[5] Arcispedale Santa Maria Nuova IRCCS, Dermatol Unit, Reggio Emilia, Italy
[6] Osped Maggiore Policlin, Fdn IRCCS Ca Granda, UO Dermatol, Milan, Italy
关键词
USTEKINUMAB;
D O I
10.2340/00015555-2698
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
In HIV-infected patients psoriasis is often severe (1) and biologic therapy may therefore be needed. However, most dermatologists are cautious when using immunosuppressive agents in patients with HIV, as these agents may reactivate or induce infection in already immuno-compromised patients (1). To date, only a few cases of HIV-infected psoriatic patients treated with biologics have been reported (2). We report here 10 cases of HIV patients treated for plaque psoriasis with biologic therapies in 6 psoriasis centres in Italy.
引用
收藏
页码:989 / 990
页数:2
相关论文
共 6 条
[1]  
Altomare G, 2014, GIORN ITAL DERMAT V, V149, P607
[2]   Use of tumor necrosis factor (TNF) inhibitors in patients with HIV/AIDS [J].
Gallitano, Stephanie M. ;
McDermott, Laura ;
Brar, Kanwaljit ;
Lowenstein, Eve .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2016, 74 (05) :974-980
[3]   TUMOR NECROSIS FACTOR-ALPHA AND INTERLEUKIN-1 STIMULATE THE HUMAN IMMUNODEFICIENCY VIRUS ENHANCER BY ACTIVATION OF THE NUCLEAR FACTOR KAPPA-B [J].
OSBORN, L ;
KUNKEL, S ;
NABEL, GJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (07) :2336-2340
[4]   Ustekinumab for the treatment of HIV psoriasis [J].
Paparizos, Vasileios ;
Rallis, Efstathios ;
Kirsten, Leuow ;
Kyriakis, Kyriakos .
JOURNAL OF DERMATOLOGICAL TREATMENT, 2012, 23 (06) :398-399
[5]   Successful treatment of ustekinumab in a severe psoriasis patient with human immunodeficiency virus infection [J].
Saeki, H. ;
Ito, T. ;
Hayashi, M. ;
Fukuchi, O. ;
Umezawa, Y. ;
Nobeyama, Y. ;
Teruya, K. ;
Nakagawa, H. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2015, 29 (08) :1653-1655
[6]   IL-23 in Infections, Inflammation, Autoimmunity and Cancer: Possible Role in HIV-1 and AIDS [J].
Yannam, Govardhana Rao ;
Gutti, Tanuja ;
Poluektova, Larisa Y. .
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2012, 7 (01) :95-112