Obesity and Hypogonadism

被引：38

作者：

Lamm, Steven ^{[1
]}

Chidakel, Aaron ^{[1
]}

Bansal, Rohan ^{[1
]}

机构：

[1] NYU, Langone Preston Robert Tisch Ctr Mens Hlth, Dept Med, 555 Madison Ave,2nd Floor, New York, NY 10022 USA

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2016年 / 43卷 / 02期

关键词：

Obesity; Hypogonadism; Testosterone; Diabetes; HORMONE-BINDING GLOBULIN; INSULIN-RESISTANCE; ADIPOSE-TISSUE; TESTOSTERONE DEFICIENCY; ANDROGEN DEFICIENCY; MUSCLE STRENGTH; BODY-WEIGHT; MEN; THERAPY; PROTEIN;

D O I：

10.1016/j.ucl.2016.01.005

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The relationship between obesity and hypogonadism is complicated. The relationship is bidirectional and there are numerous causative and correlative factors on both sides of the equation. Obesity is increasing in prevalence in epidemic proportions. Likewise, we are beginning to see the rapid increase in the incidence of male hypogonadism. It is only recently that we are learning the ways in which these 2 conditions exacerbate each other, and we are only beginning to understand how by treating one of these conditions, we can help to treat the other as well.

引用

页码：239 / +

页数：8

共 54 条

[41] Mental distress, obesity and body fat distribution in middle-aged men [J].

Rosmond, R ;

Lapidus, L ;

Marin, P ;

Bjorntorp, P .

OBESITY RESEARCH, 1996, 4 (03) :245-252

[42] Long-Term Treatment of Hypogonadal Men with Testosterone Produces Substantial and Sustained Weight Loss [J].

Saad, Farid ;

Haider, Ahmad ;

Doros, Gheorghe ;

Traish, Abdulmaged .

OBESITY, 2013, 21 (10) :1975-1981

[43] Testosterone as Potential Effective Therapy in Treatment of Obesity in Men with Testosterone Deficiency: A Review [J].

Saad, Farid ;

Aversa, Antonio ;

Isidori, Andrea M. ;

Gooren, Louis J. .

CURRENT DIABETES REVIEWS, 2012, 8 (02) :131-143

[44] Testosterone Threshold Levels and Lean Tissue Mass Targets Needed to Enhance Skeletal Muscle Strength and Function: The HORMA Trial [J].

Sattler, Fred ;

Bhasin, Shalender ;

He, Jiaxiu ;

Chou, Chih-Ping ;

Castaneda-Sceppa, Carmen ;

Yarasheski, Kevin ;

Binder, Ellen ;

Schroeder, E. Todd ;

Kawakubo, Miwa ;

Zhang, Anqi ;

Roubenoff, Ronenn ;

Azen, Stanley .

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2011, 66 (01) :122-129

[45] Resection of Nonalcoholic Steatohepatitis-Associated Hepatocellular Carcinoma: A Western Experience [J].

Shrager, Brian ;

Jibara, Ghalib A. ;

Tabrizian, Parissa ;

Roayaie, Sasan ;

Ward, Stephen C. .

INTERNATIONAL JOURNAL OF SURGICAL ONCOLOGY, 2012, 2012

[46] Novel insights in SHBG regulation and clinical implications [J].

Simo, Rafael ;

Saez-Lopez, Cristina ;

Barbosa-Desongles, Anna ;

Hernandez, Cristina ;

Selva, David M. .

TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2015, 26 (07) :376-383

[47] Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway [J].

Singh, R ;

Artaza, JN ;

Taylor, WE ;

Gonzalez-Cadavid, NF ;

Bhasin, S .

ENDOCRINOLOGY, 2003, 144 (11) :5081-5088

[48] Effect of testosterone treatment on body composition and muscle strength in men over 65 years of age [J].

Snyder, PJ ;

Peachey, H ;

Hannoush, P ;

Berlin, JA ;

Loh, L ;

Lenrow, DA ;

Holmes, JH ;

Dlewati, A ;

Santanna, J ;

Rosen, CJ ;

Strom, BL .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (08) :2647-2653

[49] Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men - Prospective results from the Massachusetts Male Aging Study [J].

Stellato, RK ;

Feldman, HA ;

Hamdy, O ;

Horton, ES ;

McKinlay, JB .

DIABETES CARE, 2000, 23 (04) :490-494

[50] Androgen deficiency and mitochondrial dysfunction: implications for fatigue, muscle dysfunction, insulin resistance, diabetes, and cardiovascular disease [J].

Traish, Abdulmaged M. ;

Abdallah, Bassima ;

Yu, George .

HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION, 2011, 8 (01) :431-444

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