The interaction between mercury(II) and sulfathiazole

被引：43
作者：
Bellú, S
Hure, E
Trapé, M
Rizzotto, M
Sutich, E
Sigrist, M
Moreno, V
机构：
[1] Univ Nacl Rosario, Area Quim Inorgan, RA-2000 Rosario, Santa Fe, Argentina
[2] Univ Nacl Rosario, Dept Microbiol, RA-2000 Rosario, Santa Fe, Argentina
[3] Univ Nacl Litoral, Fac Ingn Quim, RA-3000 Santa Fe, Argentina
[4] Univ Barcelona, Dept Quim Inorgan, E-08028 Barcelona, Spain
来源：
QUIMICA NOVA | 2003年 / 26卷 / 02期
关键词：
mercury complexes; sulfonamides; sulfonamide metal complexes;
D O I：
10.1590/S0100-40422003000200008
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The interaction of mercury(II) with sulfathiazole has been analyzed. IR and NMR spectral studies suggest a coordination of Hg(II) with the N-thiazolic atom, unlike related Hg-sulfadrugs compounds. The complex was screened for its activity against Escherichia coli, showing an appreciable antimicrobial activity compared with the ligand.
引用
收藏
页码：188 / 192
页数：5
相关论文
共 27 条
[1]  
[Anonymous], 1978, Electronic countermeasures
[2]  
[Anonymous], M100S10 NCCLS
[3]   Cobalt(II), nickel(II), and copper(II) complexes of sulfanilamide derivatives: Synthesis, spectroscopic studies, and antibacterial activity, crystal structure of [Co(sulfacetamide)(2)(NCS)(2)] [J].
Blasco, F ;
Perello, L ;
Latorre, J ;
Borras, J ;
GarciaGranda, S .
JOURNAL OF INORGANIC BIOCHEMISTRY, 1996, 61 (02) :143-154
[4]  
BULT A, 1983, METAL IONS BYOLOGICA, V16
[5]   METAL-COMPLEXES OF SULFANILAMIDE DERIVATIVES - SPECTROSCOPIC CHARACTERIZATION OF THE DICHLORO DISULFATHIAZOLE METHANOL COPPER(II) COMPLEX [J].
CASANOVA, J ;
ALZUET, G ;
BORRAS, J ;
DAVID, L ;
GATTESCHI, D .
INORGANICA CHIMICA ACTA, 1993, 211 (02) :183-186
[6]   METAL-COMPLEXES OF SULFANILAMIDE DERIVATIVES - CRYSTAL-STRUCTURE OF [ZN(SULFATHIAZOLE)2].H2O [J].
CASANOVA, J ;
ALZUET, G ;
FERRER, S ;
BORRAS, J ;
GARCIAGRANDA, S ;
PEREZCARRENO, E .
JOURNAL OF INORGANIC BIOCHEMISTRY, 1993, 51 (04) :689-699
[7]   Structural aspects of the coordination chemistry of organothallium(III) and organomercury(II) derivatives [J].
Casas, JS ;
García-Tasende, MS ;
Sordo, J .
COORDINATION CHEMISTRY REVIEWS, 1999, 193-5 :283-359
[8]   Ab initio structure determination of sulfathiazole polymorph V from synchrotron X-ray powder diffraction data [J].
Chan, FC ;
Anwar, J ;
Cernik, R ;
Barnes, P ;
Wilson, RM .
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1999, 32 :436-441
[9]   Spectroscopic behaviour of metal-drug complexes. Infrared spectra of Cu(II) complexes with 5-amino-1,3,4-thiadiazole-2-thiol(Hatm) [J].
Chufan, EE ;
Pedregosa, JC ;
Borras, J .
VIBRATIONAL SPECTROSCOPY, 1997, 15 (02) :191-199
[10]   Glutathione, albumin, cysteine, and Cys-Gly effects on toxicity and accumulation of mercuric chloride in LLC-PK1 cells [J].
Divine, KK ;
Ayala-Fierro, F ;
Barber, DS ;
Carter, DE .
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A, 1999, 57 (07) :489-505
123