Resveratrol Derivatives from Vatica albiramis

被引：17

作者：

Abe, Naohito ^{[1
]}

Ito, Tetsuro ^{[1
]}

Oyama, Masayoshi ^{[1
]}

Sawa, Ryuichi ^{[2
]}

Takahashi, Yoshikazu ^{[2
]}

Iinuma, Munekazu ^{[1
]}

机构：

[1] Gifu Pharmaceut Univ, Lab Pharmacognosy, Gifu 5011196, Japan

[2] Inst Microbial Chem, Shinagawa Ku, Tokyo 1410021, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2011年 / 59卷 / 04期

关键词：

Vatica albiramis; Dipterocarpaceae; resveratrol oligomer; structure elucidation; albiraminol; UPUNA-BORNEENSIS; STEM BARK; OLIGOMERS; PLANTS; TETRAMERS;

D O I：

10.1248/cpb.59.452

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new stilbene derivatives, albiraminols A (1) (resveratrol hexamer), B (2) (resveratrol dimer), and vatalbinoside F (3) (mono-glucoside of resveratrol dimer), along with malibatol were isolated from acetone soluble portions of the stem of Vatica albiramis. The structures of the isolates were established on the basis of spectroscopic analyses, including a detailed NMR spectroscopic investigation. The biosynthetic aspects of the isolates are discussed in this paper. Compound 1 is composed of tetrameric resveratrol (vaticanol B (1A)) and dimeric resveratrol (1B) and is the first instance of the resveratrol derivative bearing a 5,6,11,12-tetrahydro-5,11-epoxydibenzo[a,e][8]annulene ring system. Compound 2 possesses a novel 4,5-dihydro-13-oxabenzo[3,4]azuleno[7,8,1-jkl]phenanthrene skeleton in the framework.

引用

页码：452 / 457

页数：6

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