Cardiac amyloidosis as cause of sudden death

被引：0

作者：

Droeber, J. ^{[1
]}

Buschmann, C. T. ^{[2
]}

Blechschmidt, C. ^{[3
]}

Martin, H. ^{[3
]}

Tsokos, M. ^{[2
]}

机构：

[1] Brandenburg Landesinst Rechtsmed, D-14469 Potsdam, Germany

[2] Charite Univ Med Berlin, Inst Rechtsmed, Berlin, Germany

[3] Charite Univ Med Berlin, Inst Neuropathol, Berlin, Germany

来源：

RECHTSMEDIZIN | 2010年 / 20卷 / 04期

关键词：

Amyloidosis; Cardiomyopathy; Sudden death; Autopsy; Forensic histopathology; HEART;

D O I：

10.1007/s00194-010-0690-4

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

A case of sudden death of a 75-year-old woman caused by a previously undiagnosed amyloidosis with cardiac involvement is described and discussed. Due to severe narrowing of the coronary arteries, a fresh myocardial infarction was macroscopically suspected at autopsy. Microscopically, an old myocardial scar of the left cardiac wall was found with vascular and interstitial deposits of mature transthyretin (TTR) amyloid. This hereditary amyloidosis with cardiac involvement is a common clinical diagnostic finding but is a rare finding in medicolegal autopies. The gross pathology and histopathological findings are presented in supplement to the literature.

引用

页码：278 / 281

页数：4

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