Emerging Applications of Mass Spectrometry-Based Metabolic Fingerprinting in Clinics

被引：14
作者：
Cao, Jing [1 ,2 ,3 ]
Wang, Yuning [1 ,2 ,4 ]
Zhang, Yong [3 ]
Qian, Kun [1 ,2 ,4 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Biomed Engn, State Key Lab Oncogenes & Related Genes, Shanghai 200030, Peoples R China
[2] Shanghai Jiao Tong Univ, Inst Med Robot, Shanghai 200030, Peoples R China
[3] Natl Univ Singapore, Fac Engn, Dept Biomed Engn, Singapore 117583, Singapore
[4] Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Div Cardiol, 160 Pujian Rd, Shanghai 200127, Peoples R China
来源：
ADVANCED INTELLIGENT SYSTEMS | 2022年 / 4卷 / 05期
关键词：
clinics; fingerprinting; mass spectrometry; metabolites; PROFILING PROCEDURES; GAS-CHROMATOGRAPHY; LA-REIMS; SPECTROSCOPY; EXPOSURE; HEALTH; SERUM;
D O I：
10.1002/aisy.202100191
中图分类号：
TP [自动化技术、计算机技术];
学科分类号：
0812 ;
摘要：
A number of recently developed mass spectrometry (MS)-based metabolic fingerprinting analyses are promoting metabolic analysis systems into practical clinical applications, including but not limited to disease diagnosis. Herein, recent cutting-edge research on mass spectrometry-based metabolic fingerprinting analytical methodology and clinical applications are described. These developments resolve challenges regarding the practical clinical applications of MS-based metabolic fingerprinting analysis systems, such as rapid signal readout, high throughput and direct MS analysis, and intelligent data mining of complex biological samples.
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页数：8
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