Methoxsalen-induced advanced bull's eye maculopathy

被引：1

作者：

Ranjan, Ratnesh ^{[1
]}

Manayath, George J. ^{[1
]}

Salian, Romit ^{[1
]}

Narendran, Venkatapathy ^{[1
]}

机构：

[1] Aravind Eye Hosp & Postgrad Inst Ophthalmol, Dept Vitreoretina Serv, Coimbatore 641014, Tamil Nadu, India

来源：

EUROPEAN JOURNAL OF OPHTHALMOLOGY | 2021年 / 31卷 / 03期

关键词：

Methoxsalen; psoralen-ultraviolet A (PUVA) therapy; bull's eye maculopathy;

D O I：

10.1177/1120672120907317

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

A number of systemic medications are known to cause macular toxicity, and bull's eye maculopathy is caused by some of them like hydroxychloroquine and clofazimine. A 55-year-old female, known case of vitiligo with history of undergoing methoxsalen-ultraviolet A therapy, presented with painless defective vision in both eyes. Fundus examination and autofluorescence showed macular degeneration with bull's eye configuration. Optical coherence tomography showed perifoveal loss of photoreceptors and outer retinal thinning with foveal sparing appearing as 'flying saucer'. Multifocal electroretinogram showed pan-macular suppression of waveforms. Patient was diagnosed as case of methoxsalen-induced advanced macular toxicity. This is the first reported case of methoxsalen-induced advanced bull's eye maculopathy.

引用

页码：NP70 / NP73

页数：4

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