Microwave-Assisted Bronsted Acidic Ionic Liquid-Promoted One-Pot Synthesis of Heterobicyclic Dihydropyrimidinones by a Three-Component Coupling of Cyclopentanone, Aldehydes, and Urea

被引：25
作者：
Rahman, Matiur [1 ]
Majee, Adinath [1 ]
Hajra, Alakananda [1 ]
机构：
[1] Visva Bharati Univ, Dept Chem, Santini Ketan 731235, W Bengal, India
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2010年 / 47卷 / 05期
关键词：
CALCIUM-CHANNEL BLOCKERS; BIGINELLI-TYPE; INDIUM(III) CHLORIDE; SUBSTITUTED PYRROLES; SILICA-GEL; SOLVENT; SURFACE; IRRADIATION; DERIVATIVES; QUINOLINES;
D O I：
10.1002/jhet.415
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient method has been developed for the synthesis of heterobicyclic dihydropyrimidinone derivatives through a solvent-free one-pot three-component condensation of aromatic aldehydes, cyclopentanone, and urea or thiourea in the presence of Bronsted acidic ionic liquid under microwave irradiation. The catalyst can be reused at least six times without any noticeable decrease in catalytic activity.
引用
收藏
页码：1230 / 1233
页数：4
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