Association between the combined fat mass and fat-free mass index and hypertension: The Tohoku Medical Megabank Community-based Cohort Study

被引：15

作者：

Takase, Masato ^{[1
]}

Nakamura, Tomohiro ^{[1
,2
]}

Tsuchiya, Naho ^{[1
,2
]}

Kogure, Mana ^{[1
,2
]}

Itabashi, Fumi ^{[1
,2
]}

Narita, Akira ^{[1
,2
]}

Hirata, Takumi ^{[2
,3
]}

Nakaya, Naoki ^{[2
,4
]}

Hamanaka, Yohei ^{[5
]}

Sugawara, Junichi ^{[1
,6
,7
]}

Suzuki, Kichiya ^{[8
]}

Fuse, Nobuo ^{[5
,9
]}

Uruno, Akira ^{[5
]}

Kodama, Eiichi N. ^{[1
,10
]}

Kuriyama, Shinichi ^{[1
,2
,11
]}

Tsuji, Ichiro ^{[1
,2
]}

Kure, Shigeo ^{[1
,2
,12
]}

Hozawa, Atsushi ^{[1
,2
]}

机构：

[1] Tohoku Univ, Grad Sch Med, Aoba Ku, Sendai, Miyagi, Japan

[2] Tohoku Univ, Dept Prevent Med & Epidemiol, Tohoku Med Megabank Org, Aoba Ku, Sendai, Miyagi, Japan

[3] Hokkaido Univ, Dept Publ Hlth, Fac Med, Kita Ku, Sapporo, Hokkaido, Japan

[4] Saitama Prefectural Univ, Dept Hlth Sci, Saitama, Japan

[5] Tohoku Univ, Dept Integrat Genom, Tohoku Med Megabank Org, Aoba Ku, Sendai, Miyagi, Japan

[6] Tohoku Univ, Dept Community Med Supports, Tohoku Med Megabank Org, Aoba Ku, Sendai, Miyagi, Japan

[7] Tohoku Univ, Tohoku Univ Hosp, Dept Fetomaternal Med Sci, Aoba Ku, Sendai, Miyagi, Japan

[8] Tohoku Univ, Dept Biobank, Tohoku Med Megabank Org, Aoba Ku, Sendai, Miyagi, Japan

[9] Tohoku Univ, Dept Publ Relat & Planning, Tohoku Med Megabank Org, Aoba Ku, Sendai, Miyagi, Japan

[10] Tohoku Univ, Int Res Inst Disaster Sci, Dept Infect Dis, Aoba Ku, Sendai, Miyagi, Japan

[11] Tohoku Univ, Int Res Inst Disaster Sci, Dept Wct 2Disaster Publ Hlth, Aoba Ku, Sendai, Miyagi, Japan

[12] Tohoku Univ, Tohoku Univ Hosp, Dept Pediat, Aoba Ku, Sendai, Miyagi, Japan

来源：

CLINICAL AND EXPERIMENTAL HYPERTENSION | 2021年 / 43卷 / 07期

关键词：

Body composition; epidemiology; fat-free mass index; fat mass index; hypertension; BODY-FAT; INCIDENT HYPERTENSION; OBESITY; MECHANISMS; RISK;

D O I：

10.1080/10641963.2021.1925681

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Background A higher body fat percentage is associated with hypertension, even in non-obese individuals. The difference in body composition may be related to hypertension. The fat mass index (FMI) and fat-free mass index (FFMI) are proposed indicators of body composition. This study aimed to examine the relationship of a combination of FMI and FFMI with hypertension. Methods We conducted a cross-sectional study of 5,058 men and 11,842 women aged >= 20 years in the Miyagi Prefecture, northeastern Japan. The FMI and FFMI were calculated as the fat mass and fat-free mass divided by the height squared, respectively. The indices were classified into quartiles and combined into 16 groups. Hypertension was defined as casual blood pressure >= 140/90 mmHg and/or self-reported treatment for hypertension. Multivariable logistic regression models, adjusted for potential confounders, were used to assess the relationship of a combination of FMI and FFMI with hypertension. Results Higher FMI was associated with hypertension in most of the FFMI subgroups. Similarly, a higher FFMI was associated with hypertension in most of FMI subgroups. For men, the association between FFMI and hypertension in the lowest FMI group was not significant. Conclusions Reducing the FMI and FFMI may be important in preventing hypertension. For men, the relationship between the FFMI and hypertension in the lowest FMI group might be weak.

引用

页码：610 / 621

页数：12

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