Serum levels of long pentraxin PTX3 in patients with polymyalgia rheumatica

被引:0
|
作者
Pulsatelli, L.
Peri, G. [2 ]
Macchioni, P. [3 ]
Boiardi, L. [3 ]
Salvarani, C. [3 ]
Cantini, F. [4 ]
Mantovani, A. [2 ,5 ]
Meliconi, R. [1 ,6 ]
机构
[1] Ist Ortoped Rizzoli, SC Lab Immunoreumatol & Rigeneraz Tissutale, SS Reumatol, IRCCS, I-40136 Bologna, Italy
[2] IRCCS, Ist Clin Humanitas, Milan, Italy
[3] Arcispedale S Maria Nuova, Reggio Emilia, Italy
[4] Osped Prato, Prato, Italy
[5] Univ Milan, Dipartimento Med Traslaz, Milan, Italy
[6] Univ Bologna, Dipartimento Med Clin, Bologna, Italy
关键词
Polymyalgia reumatica; PTX3; biological marker; GIANT-CELL ARTERITIS; FOLLOW-UP; RELAPSE/RECURRENCE; INFECTION; INDICATOR; RECEPTOR; MARKER;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives. To evaluate PTX3 feasibility to provide a prognostic tool in PMR clinical practice. Methods. Circulating PTX3 levels were measured in 93 PMR patients at disease onset and during corticosteroid therapy and in 46 normal controls (NC) by ELISA. Results. No difference in PTX3 concentrations was observed between NC and PMR either at disease onset and during follow-up or between groups of patients defined according to the presence of recurrence/relapse. Conclusions. PTX3 serum levels do not increase significantly in active PMR. Further studies on patients with giant-cell arteritis could evaluate whether large vessel involvement may be associated to increased PTX3 levels.
引用
收藏
页码:756 / 758
页数:3
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