(E)-1-(3,5-Difluorophenyl)-3-(2,4dimethoxyphenyl)prop-2-en-1-one

被引：5

作者：

Huang, Tanxiao ^{[1
]}

Zhang, Dongdong ^{[2
]}

Yang, Quanzhi ^{[1
]}

Wei, Xiaoyan ^{[1
]}

Wu, Jianzhang ^{[1
,3
]}

机构：

[1] Wenzhou Med Coll, Sch Pharm, Wenzhou 325035, Zhejiang, Peoples R China

[2] Wenzhou Med Coll, Life Sci Coll, Wenzhou 325035, Zhejiang, Peoples R China

[3] Nanjing Univ Sci & Technol, Inst Biotechnol, Nanjing 210094, Jiangsu, Peoples R China

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2010年 / 66卷

关键词：

ANTIBACTERIAL ACTIVITY; CHALCONES; CURCUMIN; ANALOGS;

D O I：

10.1107/S1600536810035257

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title compound, C(17)H(14)F(2)O(3), is approximately planar, the dihedral angle between the rings being 5.46 (2)degrees. The H atoms of the central propenone group are trans. The crystal structure is stabilized by intermolecular C-H center dot center dot center dot F hydrogen bonds.

引用

页码：O2518 / U88

页数：12

共 16 条

[1]

[Anonymous], 2002, SMART CARD INTEGRATI

[2] (2E,5E)-2,5-bis(2-bromobenzylidene)cyclopentanone [J].

Liang, Guang ;

Tian, Ji-Lai ;

Zhao, Cheng-Guang ;

Li, Xiao-Kun .

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 :O3630-U4647

[3] Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents [J].

Liang, Guang ;

Shao, Lili ;

Wang, Yi ;

Zhao, Chengguang ;

Chu, Yanhui ;

Xiao, Jian ;

Zhao, Yu ;

Li, Xiaokun ;

Yang, Shulin .

BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (06) :2623-2631

[4] Functionalized chalcones with basic functionalities have antibacterial activity against drug sensitive Staphylococcus aureus [J].

Liu, X. L. ;

Xu, Y. J. ;

Go, M. L. .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (08) :1681-1687

[5] Antiangiogenic effects of flavonoids and chalcones [J].

Mojzis, J. ;

Varinska, L. ;

Mojzisova, G. ;

Kostova, I. ;

Mirossay, L. .

PHARMACOLOGICAL RESEARCH, 2008, 57 (04) :259-265

[6] Cationic chalcone antibiotics. Design, synthesis, and mechanism of action [J].

Nielsen, SF ;

Larsen, M ;

Boesen, T ;

Schonning, K ;

Kromann, H .

JOURNAL OF MEDICINAL CHEMISTRY, 2005, 48 (07) :2667-2677

[7] A review of anti-infective and anti-inflammatory chalcones [J].

Nowakowska, Zdzislawa .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 42 (02) :125-137

[8] 1-(4-Aminophenyl)-3-[2-(trifluoromethyl)phenyl]prop-2-en-1-one [J].

Peng, Jing ;

Xu, Huifen ;

Li, Zhe ;

Zhang, Yuyan ;

Wu, Jianzhang .

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 :O1156-U800

[9] Synthesis, SAR and antibacterial studies on novel chalcone oxazolidinone hybrids [J].

Selvakumar, N. ;

Kumar, G. Sunil ;

Azhagan, A. Malar ;

Rajulu, G. Govinda ;

Sharma, Shikha ;

Kumar, M. Sitaram ;

Das, Jagattaran ;

Iqbal, Javed ;

Trehan, Sanjay .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 42 (04) :538-543

[10]

Sheldrick G.M., 1996, SADABS

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