In Vitro and In Vivo Functional Characterization of Essence of Chicken as An Ergogenic Aid

被引:15
作者
Huang, Shih-Wei [1 ,2 ,3 ]
Hsu, Yi-Ju [1 ]
Lee, Mon-Chien [1 ]
Li, Hua-Shuai [1 ]
Yeo, Paul Chee Wei [4 ]
Lim, Ai Lin [4 ]
Huang, Chi-Chang [1 ,5 ]
机构
[1] Natl Taiwan Sports Univ, Grad Inst Sports Sci, Taoyuan 33301, Taiwan
[2] Taipei Med Univ, Shuang Ho Hosp, Dept Phys Med & Rehabil, New Taipei 23561, Taiwan
[3] Taipei Med Univ, Sch Med, Coll Med, Dept Phys Med & Rehabil, Taipei 11031, Taiwan
[4] BRANDS Suntory, Dept Sci Res & Applicat, Singapore 048423, Singapore
[5] Taipei Med Univ, Grad Inst Metab & Obes Sci, Taipei 11031, Taiwan
关键词
C2C12; anti-fatigue; anti-oxidant; exercise performance; endurance; AMINO-ACIDS; ANTIOXIDATIVE STATUS; CREATINE-KINASE; MUSCLE ATROPHY; CO-INGESTION; EXTRACT; SUPPLEMENTATION; CARNOSINE; PEPTIDES; FATIGUE;
D O I
10.3390/nu10121943
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Essence of chicken is a popular Asian nutritional supplement that is often taken to improve metabolism and general health. Although used as a traditional remedy for combating fatigue and general health, there has been few studies investigating the ergogenic properties of chicken essence and its associated mechanism. We conducted a study to investigate the anti-fatigue and anti-oxidant properties of essence of chicken (EC) after exercise. Six weeks old male Institute of Cancer Research (ICR) mice were divided to four groups (10 mice/group) and were provided different doses of Essence of Chicken (EC): (1) Vehicle (water), (2) EC-0.5X (558 mg/kg), (3) EC-1X (1117 mg/kg), and (4) EC-2X (2234 mg/kg). EC supplementation could improve endurance and grip strength (p < 0.0001) and it had significant effects on the fatigue-related biochemical markers: ammonia, blood urea nitrogen (BUN), and creatine kinase (CK) levels were significantly lowered, while glucose blood levels and lactate clearance were improved after exercise challenge. Muscle and liver glycogen levels, muscle and liver superoxide dismutase (SOD), hepatic catalase (CAT), and glutathione (GSH) levels were observed to increase with EC supplementation. Preliminary in vitro data suggests that EC may have a beneficial effect in muscle mass and strength. No abnormalities were observed from pathohistological examination. Our study suggests that the EC could significantly improve exercise performance and endurance capacity and that the anti-oxidant properties of EC may be an important contributing factor to its anti-fatigue effects.
引用
收藏
页数:22
相关论文
共 61 条
[1]   Antioxidant effects of sulfur-containing amino acids [J].
Atmaca, G .
YONSEI MEDICAL JOURNAL, 2004, 45 (05) :776-788
[2]  
AVENA RM, 1969, J BIOL CHEM, V244, P1600
[3]  
Azhar M. Z., 2001, MALAYS J PSYCHIAT, V9, P13
[4]   Antioxidant enzymes and oxidative stress adaptation to exercise training: Comparison of endurance, resistance, and concurrent training in untrained males [J].
Azizbeigi, Kamal ;
Stannard, Stephen R. ;
Atashak, Sirvan ;
Haghighi, Marjan Mosalman .
JOURNAL OF EXERCISE SCIENCE & FITNESS, 2014, 12 (01) :1-6
[5]   Creatine-Kinase- and Exercise-Related Muscle Damage Implications for Muscle Performance and Recovery [J].
Baird, Marianne F. ;
Graham, ScottM. ;
Baker, Julien S. ;
Bickerstaff, Gordon F. .
JOURNAL OF NUTRITION AND METABOLISM, 2012, 2012
[6]   Creatine kinase monitoring in sport medicine [J].
Brancaccio, Paola ;
Maffulli, Nicola ;
Limongelli, Francesco Mario .
BRITISH MEDICAL BULLETIN, 2007, 81-82 :209-230
[7]   Astaxanthin in Exercise Metabolism, Performance and Recovery: A Review [J].
Brown, Daniel R. ;
Gough, Lewis A. ;
Deb, Sanjoy K. ;
Sparks, S. Andy ;
McNaughton, Lars R. .
FRONTIERS IN NUTRITION, 2018, 4
[8]  
Burattini S, 2004, EUR J HISTOCHEM, V48, P223
[9]   Lactic acid and exercise performance - Culprit or friend? [J].
Cairns, SP .
SPORTS MEDICINE, 2006, 36 (04) :279-291
[10]   Glutamine and carbohydrate supplements reduce ammonemia increase during endurance field exercise [J].
Carvalho-Peixoto, Jacqueline ;
Alves, Robson Cardilo ;
Cameron, Luiz-Claudio .
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM, 2007, 32 (06) :1186-1190