Effects of glimepiride and glibenclamide on carotid atherosclerosis in type 2 diabetic patients

被引：7
|
作者：
Katakami, Naoto [1 ]
Kaneto, Hideaki [1 ]
Matsuhisa, Munehide [2 ]
Shimomura, Iichiro [1 ]
Yamasaki, Yoshimitsu [3 ]
机构：
[1] Osaka Univ, Grad Sch Med, Dept Metab Med, Suita, Osaka 5650871, Japan
[2] Univ Tokushima, Diabet Therapeut & Res Ctr, Tokushima, Japan
[3] Osaka Univ, Ctr Adv Sci & Innovat, Suita, Osaka 565, Japan
来源：
DIABETES RESEARCH AND CLINICAL PRACTICE | 2011年 / 92卷 / 01期
关键词：
IMT; Carotid atherosclerosis; Glimepiride; Glibenclamide; INTIMA-MEDIA THICKNESS; ARTERY-DISEASE; RISK;
D O I：
10.1016/j.diabres.2010.12.023
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We performed a 3-year observation study of type 2 diabetic patients treated with glibenclamide or glimepiride and found that the annual progression of the maximum carotid intima-media thickness was significantly attenuated in the subjects treated with glimepiride (n = 20) as compared with those treated with glibenclamide (n = 20) (-0.044 +/- 0.171 mm/year vs. 0.077 +/- 0.203 mm/year, p = 0.0474). (C) 2010 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：E20 / E22
页数：3
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