Artery and vein formation: a tug of war between different forces

被引:42
作者
Lin, Fu-Jung
Tsai, Ming-Jer
Tsai, Sophia Y. [1 ]
机构
[1] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA
[2] Baylor Coll Med, Program Dev Biol, Houston, TX 77030 USA
关键词
arterial-venous specification; COUP; TFII; notch signalling; PI3K; Vegf;
D O I
10.1038/sj.embor.7401076
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
How arterial and venous fates are established is largely unknown. In the past, circulatory dynamics were thought to be the exclusive cause of arteries and veins being structurally and functionally distinct; however, growing evidence indicates that an orderly progression of molecular signals controls arterial-venous specification in the developing vertebrate vascular system.
引用
收藏
页码:920 / 924
页数:5
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