Phenotyping Alzheimer's disease with blood tests

被引：31
作者：
Blennow, Kaj [1 ]
机构：
[1] Gothenburg Univ, Sahlgrenska Acad, Inst Neurosci & Physiol, Clin Neurochem Lab, Molndal, Sweden
来源：
SCIENCE | 2021年 / 373卷 / 6555期
关键词：
PERFORMANCE; TAU;
D O I：
10.1126/science.abi5208
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
[No abstract available]
引用
收藏
页码：626 / 628
页数：3
相关论文
共 15 条
[1]   Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology [J].
Ashton, Nicholas J. ;
Pascoal, Tharick A. ;
Karikari, Thomas K. ;
Benedet, Andrea L. ;
Lantero-Rodriguez, Juan ;
Brinkmalm, Gunnar ;
Snellman, Anniina ;
Scholl, Michael ;
Troakes, Claire ;
Hye, Abdul ;
Gauthier, Serge ;
Vanmechelen, Eugeen ;
Zetterberg, Henrik ;
Rosa-Neto, Pedro ;
Blennow, Kaj .
ACTA NEUROPATHOLOGICA, 2021, 141 (05) :709-724
[2]   Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer's disease [J].
Barthelemy, Nicolas R. ;
Horie, Kanta ;
Sato, Chihiro ;
Bateman, Randall J. .
JOURNAL OF EXPERIMENTAL MEDICINE, 2020, 217 (11)
[3]   Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease [J].
Chatterjee, Pratishtha ;
Pedrini, Steve ;
Stoops, Erik ;
Goozee, Kathryn ;
Villemagne, Victor L. ;
Asih, Prita R. ;
Verberk, Inge M. W. ;
Dave, Preeti ;
Taddei, Kevin ;
Sohrabi, Hamid R. ;
Zetterberg, Henrik ;
Blennow, Kaj ;
Teunissen, Charlotte E. ;
Vanderstichele, Hugo M. ;
Martins, Ralph N. .
TRANSLATIONAL PSYCHIATRY, 2021, 11 (01)
[4]   Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling data from four cohorts [J].
Karikari, Thomas K. ;
Pascoal, Tharick A. ;
Ashton, Nicholas J. ;
Janelidze, Shorena ;
Benedet, Andrea Lessa ;
Rodriguez, Juan Lantero ;
Chamoun, Mira ;
Savard, Melissa ;
Kang, Min Su ;
Therriault, Joseph ;
Scholl, Michael ;
Massarweh, Gassan ;
Soucy, Jean-Paul ;
Hoglund, Kina ;
Brinkmalm, Gunnar ;
Mattsson, Niklas ;
Palmqvist, Sebastian ;
Gauthier, Serge ;
Stomrud, Erik ;
Zetterberg, Henrik ;
Hansson, Oskar ;
Rosa-Neto, Pedro ;
Blennow, Kaj .
LANCET NEUROLOGY, 2020, 19 (05) :422-433
[5]   Population-based blood screening for preclinical Alzheimer's disease in a British birth cohort at age 70 [J].
Keshavan, Ashvini ;
Pannee, Josef ;
Karikari, Thomas K. ;
Rodriguez, Juan Lantero ;
Ashton, Nicholas J. ;
Nicholas, Jennifer M. ;
Cash, David M. ;
Coath, William ;
Lane, Christopher A. ;
Parker, Thomas D. ;
Lu, Kirsty ;
Buchanan, Sarah M. ;
Keuss, Sarah E. ;
James, Sarah-Naomi ;
Murray-Smith, Heidi ;
Wong, Andrew ;
Barnes, Anna ;
Dickson, John C. ;
Heslegrave, Amanda ;
Portelius, Erik ;
Richards, Marcus ;
Fox, Nick C. ;
Zetterberg, Henrik ;
Blennow, Kaj ;
Schott, Jonathan M. .
BRAIN, 2021, 144 (02) :434-449
[6]   Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography [J].
Mielke, Michelle M. ;
Hagen, Clinton E. ;
Xu, Jing ;
Chai, Xiyun ;
Vemuri, Prashanthi ;
Lowe, Val J. ;
Airey, David C. ;
Knopman, David S. ;
Roberts, Rosebud O. ;
Machulda, Mary M. ;
Jack, Clifford R., Jr. ;
Petersen, Ronald C. ;
Dage, Jeffrey L. .
ALZHEIMERS & DEMENTIA, 2018, 14 (08) :989-997
[7]   High performance plasma amyloid-β biomarkers for Alzheimer's disease [J].
Nakamura, Akinori ;
Kaneko, Naoki ;
Villemagne, Victor L. ;
Kato, Takashi ;
Doecke, James ;
Dore, Vincent ;
Fowler, Chris ;
Li, Qiao-Xin ;
Martins, Ralph ;
Rowe, Christopher ;
Tomita, Taisuke ;
Matsuzaki, Katsumi ;
Ishii, Kenji ;
Ishii, Kazunari ;
Arahata, Yutaka ;
Iwamoto, Shinichi ;
Ito, Kengo ;
Tanaka, Koichi ;
Masters, Colin L. ;
Yanagisawa, Katsuhiko .
NATURE, 2018, 554 (7691) :249-+
[8]   NFL is a marker of treatment response in children with SMA treated with nusinersen [J].
Olsson, Bob ;
Alberg, Lars ;
Cullen, Nicholas C. ;
Michael, Eva ;
Wahlgren, Lisa ;
Kroksmark, Anna-Karin ;
Rostasy, Kevin ;
Blennow, Kaj ;
Zetterberg, Henrik ;
Tulinius, Mar .
JOURNAL OF NEUROLOGY, 2019, 266 (09) :2129-2136
[9]   Prediction of future Alzheimer's disease dementia using plasma phospho-tau combined with other accessible measures [J].
Palmqvist, Sebastian ;
Tideman, Pontus ;
Cullen, Nicholas ;
Zetterberg, Henrik ;
Blennow, Kaj ;
Dage, Jeffery L. ;
Stomrud, Erik ;
Janelidze, Shorena ;
Mattsson-Carlgren, Niklas ;
Hansson, Oskar .
NATURE MEDICINE, 2021, 27 (06) :1034-+
[10]   Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders [J].
Palmqvist, Sebastian ;
Janelidze, Shorena ;
Quiroz, Yakeel T. ;
Zetterberg, Henrik ;
Lopera, Francisco ;
Stomrud, Erik ;
Su, Yi ;
Chen, Yinghua ;
Serrano, Geidy E. ;
Leuzy, Antoine ;
Mattsson-Carlgren, Niklas ;
Strandberg, Olof ;
Smith, Ruben ;
Villegas, Andres ;
Sepulveda-Falla, Diego ;
Chai, Xiyun ;
Proctor, Nicholas K. ;
Beach, Thomas G. ;
Blennow, Kaj ;
Dage, Jeffrey L. ;
Reiman, Eric M. ;
Hansson, Oskar .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 324 (08) :772-781
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