Three cerebrosides from the sea cucumber Cucumaria frondosa

被引：9
作者：
La Ming-Ping [1 ]
Shao Jun-Jie [2 ]
Jiao Jian [2 ]
Yi Yang-Hua [1 ]
机构：
[1] Second Mil Med Univ, Res Ctr Marine Drugs, Shanghai 200433, Peoples R China
[2] Dalian Haiyantang Biol Co Ltd, Dalian 116021, Peoples R China
来源：
CHINESE JOURNAL OF NATURAL MEDICINES | 2012年 / 10卷 / 02期
关键词：
Glycosphingolipids; Cerebrosides; Sea Cucumber; Cucumaria frondosa; HOLOTHUROIDEA; CONSTITUENTS;
D O I：
10.3724/SP.J.1009.2012.00105
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
AIM: To study the chemical constituents of the sea cucumber Cucumaria frondosa. METHOD: Three sphingosine-type glucocerebrosides, CF-3-1, CF-3-2 and CF-3-3 were isolated by means of high performance liquid chromatography (HPLC) from a cerebroside molecular species 3 which was obtained from the less polar fraction of the 65% EtOH extract of the sea cucumber Cucumaria frondosa Gunnerus. RESULT: The structures of these cerebrosides were determined on the basis of chemical and spectroscopic evidences. CONCLUSION: Three compounds were isolated from the sea cucumber Cucumaria frondosa for the first time. CF-3-3 and CF-3-2 were obtained as pure compounds for the first time.
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收藏
页码：105 / 109
页数：5
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