Modulations of high-voltage activated Ca2+ channels in the central neurones of Spodoptera exigua by chlorantraniliprole

被引：39

作者：

Li, Yuxin ^{[1
]}

Mao, Mingzhen ^{[1
]}

Li, Yiming ^{[1
]}

Xiong, Lixia ^{[1
]}

Li, Zhengming ^{[1
]}

Xu, Junying ^{[1
]}

机构：

[1] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

PHYSIOLOGICAL ENTOMOLOGY | 2011年 / 36卷 / 03期

关键词：

Calcium channel; chlorantraniliprole; neurones; Spodoptera exigua; whole-cell patch-clamp; ANTHRANILIC DIAMIDE; RELEASE; INSECTICIDES; MODE;

D O I：

10.1111/j.1365-3032.2011.00788.x

中图分类号：

Q96 [昆虫学];

学科分类号：

摘要：

The modulation of voltage-gated calcium channels by chlorantraniliprole in the central neurones isolated from third-instar larvae of Spodoptera exigua is studied by the whole-cell patch-clamp technique. The current of calcium in the third-instar larvae of S. exigua is identified as a high-voltage activated Ca2+ current. During the 10-min recording, the current-voltage relationship curves of whole-cell calcium channels are shifted in a negative direction by 10 mV compared with the control group. The fact that the gravity rundown of calcium current in the treated group is more apparent than in the control group demonstrates that the open channels are constantly inactivated. In addition, chlorantraniliprole inhibits the recorded calcium currents in a concentration-dependent manner, which is irreversible on washout.

引用

页码：230 / 234

页数：5

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