Is a two-step glutamate dehyrogenase antigen-cytotoxicity neutralization assay algorithm superior to the premier toxin a and B enzyme immunoassay for laboratory detection of Clostridium difficile?

被引：75

作者：

Gilligan, Peter H. ^{[1
,2
]}

机构：

[1] Univ N Carolina Hosp, Clin Microbiol Immunol Labs, Chapel Hill, NC 27514 USA

[2] Univ N Carolina, Sch Med, Pathol Lab Med, Chapel Hill, NC 27514 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2008年 / 46卷 / 04期

关键词：

D O I：

10.1128/JCM.02100-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A two-step algorithm for the detection of Clostridium difficile by the use of C. Diff Quik Chek (TechLab, Blacksburg, VA) and a tissue culture cytotoxicity neutralization assay was found to be more sensitive than the widely used solid-phase enzyme immunoassay (EIA), the Premier toxin A and B EIA (Meridian Bioscience, Cincinnati, OH), and a newly developed, rapid single-test EIA for C. difficile toxins A and B (Tox A/B Quik Chek; TechLab).

引用

页码：1523 / 1525

页数：3

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