What the pulmonary specialist should know about the new inhalation therapies

被引:554
作者
Laube, B. L. [1 ]
Janssens, H. M. [2 ]
de Jongh, F. H. C. [3 ]
Devadason, S. G. [4 ]
Dhand, R. [5 ]
Diot, P. [6 ]
Everard, M. L. [7 ]
Horvath, I. [8 ]
Navalesi, P. [9 ]
Voshaar, T. [10 ]
Chrystyn, H. [11 ]
机构
[1] Johns Hopkins Univ, Sch Med, Dept Paediat, Baltimore, MD 21287 USA
[2] Erasmus MC Sophia Childrens Hosp, Rotterdam, Netherlands
[3] Med Spectrum Twente, Pulmonol, Enschede, Netherlands
[4] Univ Western Australia, Sch Paediat & Child Hlth, Perth, WA 6009, Australia
[5] Univ Missouri, Columbia, MO USA
[6] Hop Bretonneau, INSERM, U618, Tours, France
[7] Sheffield Childrens Hosp, Sheffield, S Yorkshire, England
[8] Semmelweis Univ, Dept Pulmonol, Budapest, Hungary
[9] Univ Piemonte Orientale, Osped St Andrea Anaesthesia & Intens Care, Vercelli, Italy
[10] Krankenhaus Bethanien Moers, Interdisciplinary Lung Ctr, Moers, Germany
[11] Univ Huddersfield, Div Pharm & Pharmaceut Sci, Sch Appl Sci, Huddersfield HD1 3DH, W Yorkshire, England
关键词
Inhalation technique; inhalation therapy; inhalation treatment; pulmonary delivery; METERED-DOSE INHALER; AIR-FLOW OBSTRUCTION; DRY-POWDER INHALER; MECHANICALLY VENTILATED PATIENTS; AEROSOL BRONCHODILATOR DELIVERY; RESPIRATORY-DISTRESS-SYNDROME; PARTICLE-SIZE DISTRIBUTION; CYSTIC-FIBROSIS; IN-VITRO; LUNG DEPOSITION;
D O I
10.1183/09031936.00166410
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
A collaboration of multidisciplinary experts on the delivery of pharmaceutical aerosols was facilitated by the European Respiratory Society (ERS) and the International Society for Aerosols in Medicine (ISAM), in order to draw up a consensus statement with clear, up-to-date recommendations that enable the pulmonary physician to choose the type of aerosol delivery device that is most suitable for their patient. The focus of the consensus statement is the patient-use aspect of the aerosol delivery devices that are currently available. The subject was divided into different topics, which were in turn assigned to at least two experts. The authors searched the literature according to their own strategies, with no central literature review being performed. To achieve consensus, draft reports and recommendations were reviewed and voted on by the entire panel. Specific recommendations for use of the devices can be found throughout the statement. Healthcare providers should ensure that their patients can and will use these devices correctly. This requires that the clinician: is aware of the devices that are currently available to deliver the prescribed drugs; knows the various techniques that are appropriate for each device; is able to evaluate the patient's inhalation technique to be sure they are using the devices properly; and ensures that the inhalation method is appropriate for each patient.
引用
收藏
页码:1308 / 1331
页数:24
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