Crystal and molecular structure of 13-diethanolamino-deacetyllaurenobiolide. Macrocycle conformation in linear germacrolides

被引：1

作者：

Tashkhodzhaev, B ^{[1
]}

Sham'yanov, ID

Izbosarov, MB

Antipin, MY

机构：

[1] Acad Sci Republ Uzbekistan, S Yu Yunusov Inst Chem Plant Subst, Tashkent, Uzbekistan

[2] Tashkent Pharmaceut Inst, Tashkent 700015, Uzbekistan

[3] Russian Acad Sci, Inst Elementorgan Cpds, Moscow 117813, Russia

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2004年 / 40卷 / 06期

关键词：

sesquiterpene lactone; germacranolide; 13-diethanolamino-deacetyllaurenobiolide; x-ray structure analysis;

D O I：

10.1007/s10600-005-0034-x

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An x-ray structure analysis of the 13-diethanolamino derivative of deacetyllaurenobiolide, a germacrane sesquiterpene lactone, was performed. The germacrane macrocycle has the chairchair conformation with the (D5,1D14)-D-15 configuration. The conformation of the macrocycle in linear germacrolides was analyzed.

引用

页码：552 / 556

页数：5

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