Fatal Pulmonary Mucormycosis due to Rhizopus homothallicus

被引:7
作者
Compain, Fabrice [1 ]
Ait-Ammar, Nawel [2 ,5 ]
Botterel, Francoise [2 ,5 ]
Gibault, Laure [3 ]
Le Pimpec Barthes, Francoise [4 ]
Dannaoui, Eric [1 ,5 ]
机构
[1] Univ Paris 05, Hop Europeen Georges Pompidou, AP HP, Unite Parasitol Mycol,Serv Microbiol,Fac Med, Paris, France
[2] Hop Henri Mondor, AP HP, DHU VIC, Unite Mycol Parasitol,Dept Bacteriol Virol Hyg Pa, Creteil, France
[3] Hop Europeen Georges Pompidou, AP HP, Dept Pathol, Paris, France
[4] Hop Europeen Georges Pompidou, AP HP, Dept Thorac Surg, Paris, France
[5] Univ Paris Est Creteil, IMRB, Fac Med, Dynamyc Res Grp, Creteil, France
关键词
Rhizopus homothallicus; Case report; Mucorales; Mucormycosis; Molecular sequence data; FUNGAL-INFECTIONS; SALVAGE THERAPY; AMPHOTERICIN-B; ZYGOMYCOSIS; DIAGNOSIS; POSACONAZOLE; IDENTIFICATION; EPIDEMIOLOGY; MANAGEMENT; MORTALITY;
D O I
10.1007/s11046-017-0151-7
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We report here a case of cavitary pneumonia due to Rhizopus homothallicus in a diabetic patient. This is the first proven case of R. homothallicus infection in Western countries and the third case described worldwide. The organism was isolated from lung biopsy and identified after amplification and sequencing of the internal transcribed spacer region.
引用
收藏
页码:907 / 913
页数:7
相关论文
共 37 条
[1]   A Molecular Phylogeny-Based Taxonomy of the Genus Rhizopus [J].
Abe, Ayumi ;
Asano, Kozo ;
Sone, Teruo .
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2010, 74 (07) :1325-1331
[2]   Stability in the cumulative incidence, severity and mortality of 101 cases of invasive mucormycosis in high-risk patients from 1995 to 2011: a comparison of eras immediately before and after the availability of voriconazole and echinocandin-amphotericin combination therapies [J].
Abidi, Maheen Z. ;
Sohail, Muhammad R. ;
Cummins, Nathan ;
Wilhelm, Mark ;
Wengenack, Nancy ;
Brumble, Lisa ;
Shah, Harshal ;
Hata, Donna Jane ;
McCullough, Ann ;
Wendel, Amy ;
Vikram, Holenarasipur R. ;
Kusne, Shimon ;
Litzow, Mark ;
Letendre, Louis ;
Lahr, Brian D. ;
Poeschla, Eric ;
Walker, Randall C. .
MYCOSES, 2014, 57 (11) :687-698
[3]   Spectrum of Zygomycete Species Identified in Clinically Significant Specimens in the United States [J].
Alvarez, E. ;
Sutton, D. A. ;
Cano, J. ;
Fothergill, A. W. ;
Stchigel, A. ;
Rinaldi, M. G. ;
Guarro, J. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2009, 47 (06) :1650-1656
[4]   Sequence-Based Identification of Aspergillus, Fusarium, and Mucorales Species in the Clinical Mycology Laboratory: Where Are We and Where Should We Go from Here? [J].
Balajee, S. A. ;
Borman, A. M. ;
Brandt, M. E. ;
Cano, J. ;
Cuenca-Estrella, M. ;
Dannaoui, E. ;
Guarro, J. ;
Haase, G. ;
Kibbler, C. C. ;
Meyer, W. ;
O'Donnell, K. ;
Petti, C. A. ;
Rodriguez-Tudela, J. L. ;
Sutton, D. ;
Velegraki, A. ;
Wickes, B. L. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2009, 47 (04) :877-884
[5]   Population-Based Analysis of Invasive Fungal Infections, France, 2001-2010 [J].
Bitar, Dounia ;
Lortholary, Olivier ;
Le Strat, Yann ;
Nicolau, Javier ;
Coignard, Bruno ;
Tattevin, Pierre ;
Che, Didier ;
Dromer, Francoise .
EMERGING INFECTIOUS DISEASES, 2014, 20 (07) :1149-1155
[6]   The rising trend of invasive zygomycosis in patients with uncontrolled diabetes mellitus [J].
Chakrabarti, Arunaloke ;
Das, Ashim ;
Mandal, Jharna ;
Shivaprakash, M. R. ;
George, Varghese K. ;
Tarai, Bansidhar ;
Rao, Pooja ;
Panda, Naresh ;
Verma, Subhash C. ;
Sakhuja, Vinay .
MEDICAL MYCOLOGY, 2006, 44 (04) :335-342
[7]   Mucormycosis in India: unique features [J].
Chakrabarti, Arunaloke ;
Singh, Rachna .
MYCOSES, 2014, 57 :85-90
[8]   Cavitary Pulmonary Zygomycosis Caused by Rhizopus homothallicus [J].
Chakrabarti, Arunaloke ;
Marak, Rungmei S. K. ;
Shivaprakash, M. R. ;
Gupta, Sunita ;
Garg, Rajiv ;
Sakhuja, V. ;
Singhal, Sanjay ;
Baghela, Abhishek ;
Dixit, Ajai ;
Garg, M. K. ;
Padhye, Arvind A. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2010, 48 (05) :1965-1969
[9]   Delaying amphotericin B-based frontline therapy significantly increases mortality among patients with Hematologic malignancy who have zygomycosis [J].
Chamilos, Georgios ;
Lewis, Russell E. ;
Kontoyiannis, Dimitrios P. .
CLINICAL INFECTIOUS DISEASES, 2008, 47 (04) :503-509
[10]   ESCMID† and ECMM‡ joint clinical guidelines for the diagnosis and management of mucormycosis 2013 [J].
Cornely, O. A. ;
Arikan-Akdagli, S. ;
Dannaoui, E. ;
Groll, A. H. ;
Lagrou, K. ;
Chakrabarti, A. ;
Lanternier, F. ;
Pagano, L. ;
Skiada, A. ;
Akova, M. ;
Arendrup, M. C. ;
Boekhout, T. ;
Chowdhary, A. ;
Cuenca-Estrella, M. ;
Freiberger, T. ;
Guinea, J. ;
Guarro, J. ;
de Hoog, S. ;
Hope, W. ;
Johnson, E. ;
Kathuria, S. ;
Lackner, M. ;
Lass-Floerl, C. ;
Lortholary, O. ;
Meis, J. F. ;
Meletiadis, J. ;
Munoz, P. ;
Richardson, M. ;
Roilides, E. ;
Tortorano, A. M. ;
Ullmann, A. J. ;
van Diepeningen, A. ;
Verweij, P. ;
Petrikkos, G. .
CLINICAL MICROBIOLOGY AND INFECTION, 2014, 20 :5-26