CYTOTOXIC ACTIVITY OF ε-AMINOCAPROYLAMINO ACIDS IN BREAST CANCER MCF-7 AND FIBROBLAST CELL LINES

被引：0

作者：

Midura-Nowaczek, Krystyna ^{[1
]}

Markowska, Agnieszka ^{[1
]}

Krajewska, Dorota ^{[1
]}

Wolczynski, Slawomir ^{[2
]}

机构：

[1] Med Univ Bialystok, Dept Organ Chem, PL-15223 Bialystok, Poland

[2] Med Univ Bialystok, Dept Gynecol Endocrinol, PL-15276 Bialystok, Poland

来源：

ACTA POLONIAE PHARMACEUTICA | 2010年 / 67卷 / 02期

关键词：

epsilon-aminocaproylamino acids; cytotoxity; MCF-7; fibroblast cells; antibacterial activity; AMINO-ACIDS; THYMOCYTE APOPTOSIS; PLASMIN-INHIBITOR; DERIVATIVES; GROWTH; YO-2;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effect of H-EACA-L-Cys(S-Bzl)-OH, H-EACA-L-Leu-OH. H-EACA-L-Nle-OH and EACA on the viability of MCF-7 and fibroblast cells was examined. The antibacterial activity of these compounds was also tested. H-EACA-L-Leu-OH and H-EACA-L-Nle-OH showed cytotoxic activity against MCF-7 and fibroblast cell lines, particularly in the highest studied 20 mM concentration. None of the examined dipeptides showed antibacterial activity.

引用

页码：201 / 204

页数：4

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