The interplay between environmental factors, vector competence and vaccine immunodynamics as possible explanation of the 2019 yellow fever re-emergence in Nigeria

被引：6

作者：

Abdullahi, I. N. ^{[1
]}

Anka, A. U. ^{[1
]}

Emeribe, A. U. ^{[2
]}

Umar, K. ^{[1
]}

Adekola, H. A. ^{[3
]}

Uzairue, L. ^{[4
]}

Ghmaba, P. E. ^{[5
]}

Okwume, C. C. ^{[6
]}

机构：

[1] Ahmadu Bello Univ, Dept Med Lab Sci, Fac Allied Hlth Sci, Coll Med Sci, PMB 05 Samaru, Zaria, Nigeria

[2] Univ Calabar, Dept Med Lab Sci, Fac Allied Med Sci, Calabar, Nigeria

[3] Olabisi Onabanjo Univ, Dept Microbiol, Ago Iwoye, Ogun State, Nigeria

[4] Fed Univ, Dept Med Lab Sci, Oye, Ekiti, Nigeria

[5] Univ Maiduguri Teaching Hosp, WHO Natl Polio Reference Lab, Maiduguri, Nigeria

[6] Univ Nigeria Teaching Hosp, Dept Med Lab Serv, Enugu, Nigeria

来源：

NEW MICROBES AND NEW INFECTIONS | 2021年 / 41卷

关键词：

Genetics; Nigeria; reemergence; vaccination; yellow fever; BOOSTER VACCINATION; VIRUS; IMMUNITY; RECOMMENDATIONS; IMMUNOGENICITY; ANTIBODIES; OUTBREAK; THREAT; RISK; 17D;

D O I：

10.1016/j.nmni.2021.100858

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Throughout the year 2019, Nigeria had sporadic outbreaks of yellow fever (YF), which began in the northern region of the country. Indeed, controlling the bites and population of Aedes mosquitoes and vaccination are the only effective means of preventing YF. Vectorial migration, sylvan-to-urban spillover, immunization failure and, perhaps, genetic modification of YFV could be reasons for the re-emergence of YF at the community, state and national levels. This article offers a critical review of the vector biology, YF vaccine immunodynamics and environmental drivers of YFV infections, with the aim of understanding the interplay of these factors in the re-emergence of YF and risk assessment of living in or travelling to areas where YF is endemic. (c) 2021 The Author(s). Published by Elsevier Ltd.

引用

页数：10

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