First-episode schizophreniform disorder: comparisons with first-episode schizophrenia

被引:19
作者
Zarate, CA
Tohen, M
Land, ML
机构
[1] Univ Massachusetts, Sch Med, Bipolar & Psychot Disorders Program, Worcester, MA 01655 USA
[2] Harvard Univ, Sch Med, Int Control Consortium Bipolar Disorder Res, Boston, MA USA
[3] Harvard Univ, Sch Med, McLean Psychosis Project 1, Consolidated Dept Psychiat, Boston, MA USA
[4] Harvard Univ, Sch Med, Program Neurosci, Boston, MA USA
[5] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[6] McLean Hosp, Bipolar & Psychot Disorders Program, Belmont, MA 02178 USA
[7] Lilly Res Labs, Indianapolis, IN USA
关键词
epidemiology; outcome; psychosis; schizophrenia; schizophreniform;
D O I
10.1016/S0920-9964(00)00031-1
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: Schizophreniform disorder remains poorly understood and has been reported probably to be a heterogeneous group of psychotic disorders. Method: This study compared first-episode schizophreniform disorder (N=12) and schizophrenia (N=18) patients. The authors propose that schizophreniform disorder has a different type of onset and outcome than schizophrenia. Patients were given extensive assessments at initial evaluation, 6 month follow-up, and 24 month follow-up. Comparisons between the two groups were made on type of onset, demographic. clinical ratings and outcome variables. Results: Patients with schizophreniform disorder compared to patients with schizophrenia were more likely to have an acute onset (P=0.003), and have recovered by 6 months (P=0.03). However, there were no differences in outcome at 24 months. Furthermore, all schizophreniform cases except for two were re-diagnosed at 24 months: as having schizophrenia. Conclusions: The findings suggest that the initial differences of schizophreniform disorder compared to schizophrenia were not apparent at 24 months follow-up. Schizophreniform disorder did not emerge as a highly distinctive and stable form of psychosis that merits a diagnostic classification separate From schizophrenia. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:31 / 34
页数:4
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