Asymmetric cooperativity in tandem hybridization of enantiomeric metal complex-tethered short fluorescent DNA probes

被引：21

作者：

Kitamura, Y

Ihara, T

Okada, K

Tsujimura, Y

Shirasaka, Y

Tazaki, M

Jyo, A

机构：

[1] Kumamoto Univ, Dept Appl Chem & Biochem, Kumamoto 8608555, Japan

[2] JST, PRESTO, Kawaguchi, Saitama 3320012, Japan

[3] Sojo Univ, Fac Engn, Kumamoto 8600082, Japan

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 36期

关键词：

D O I：

10.1039/b505632b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The complex [Ru(phen)(2)(dppz)](2+) (phen=1,10-phenanthroline, dppz=dipyrido[3,2-a:2',3'-c]phenazine) was attached to the 5' end of a short oligonucleotide to form conjugates, the Delta-isomer of which showed a high cooperativity during the recognition of the repetitive sequence, while the Lambda-isomer did not.

引用

页码：4523 / 4525

页数：3

共 23 条

[21] How easily oxidizable is DNA? One-electron reduction potentials of adenosine and guanosine radicals in aqueous solution [J].