Gold in Total Synthesis: Alkynes as Carbonyl Surrogates

被引：82

作者：

Brenzovich, William E., Jr. ^{[1
]}

机构：

[1] Roanoke Coll, Dept Chem, Salem, VA 24153 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 36期

关键词：

cyclization; gold; homogeneous catalysis; total synthesis; synthetic methods; CATALYZED SYNTHESIS; HYDRATION; 5,5-SPIROKETALS; COMPLEXES; LIGAND; ACID;

D O I：

10.1002/anie.201204598

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fields of gold: Recent developments in the field of gold catalysis, using an alkyne as a carbonyl equivalent is becoming an important chemical transformation, thus providing flexibility in synthetic planning of complex and sensitive natural products. Understanding of the reaction and new catalyst designs are providing new conditions that are amenable for late-stage synthetic intermediates. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：8933 / 8935

页数：3

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