The Two Major Epidemics of the Twenty-First Century: Obesity and Cancer

被引：62

作者：

Kaidar-Person, Orit ^{[2
,3
]}

Bar-Sela, Gil ^{[2
,3
]}

Person, Benjamin ^{[1
,3
]}

机构：

[1] Technion Israel Inst Technol, Dept Gen Surg, IL-31096 Haifa, Israel

[2] Technion Israel Inst Technol, Div Oncol, IL-31096 Haifa, Israel

[3] Technion Israel Inst Technol, Rappaport Fac Med, IL-31096 Haifa, Israel

来源：

OBESITY SURGERY | 2011年 / 21卷 / 11期

关键词：

Obesity; Insulin resistance; Metabolic syndrome; Cancer; Surgery; Bariatric; BODY-MASS INDEX; FAT DIETARY PATTERN; BREAST-CANCER; COLORECTAL-CANCER; POSTMENOPAUSAL WOMEN; METABOLIC SYNDROME; RECTAL-CANCER; WEIGHT CHANGE; SEX-HORMONES; COLON-CANCER;

D O I：

10.1007/s11695-011-0490-2

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

It is a well-known fact that severe obesity is associated with the metabolic syndrome, type 2 diabetes, cardiovascular disease, hypertension, and other diseases. Epidemiological studies have suggested that obesity is also associated with increased risk of several cancer types. The number of people who are suffering from severe obesity is growing, and clinical data suggest that severely obese patients belong to a unique population with regards to risk, efficacy of screening, and cancer treatment. This review will point out the potential mechanism linking obesity and cancer and will discuss several challenges in various treatment modalities of cancer in obese patients.

引用

页码：1792 / 1797

页数：6

共 74 条

[1] Actual body weight for determining doses of chemotherapy in obese cancer patients - Evaluation of treatment tolerability [J].