Recommendations and guidelines for the treatment of Clostridioides difficile infection in Taiwan

被引：23

作者：

Wu, Kuan-Sheng ^{[1
,2
]}

Syue, Ling-Shan ^{[3
]}

Cheng, Aristine ^{[4
,5
]}

Yen, Ting-Yu ^{[6
]}

Chen, Hsien-Meng ^{[7
]}

Chiu, Yu-Hsin ^{[8
]}

Hsu, Yu-Lung ^{[9
]}

Chiu, Chun-Hsiang ^{[10
]}

Su, Ting-Yi ^{[11
]}

Tsai, Wan-Lin ^{[12
]}

Chen, Wei-Yu ^{[13
]}

Huang, Chung-Hao ^{[14
]}

Hung, Huei-Min ^{[15
]}

Huang, Ling-Ju ^{[16
]}

Kuo, Hong-Jie ^{[17
]}

Lin, Pei-Chin ^{[18
,19
]}

Yang, Ching-Hsiang ^{[20
]}

Hong, Pi-Lien ^{[20
]}

Lee, Susan Shin-Jung ^{[1
,2
]}

Chen, Yao-Shen ^{[1
,2
]}

Liu, Yung-Ching ^{[21
]}

Huang, Li-Ming ^{[6
]}

机构：

[1] Kaohsiung Vet Gen Hosp, Dept Internal Med, Div Infect Dis, Kaohsiung, Taiwan

[2] Natl Yang Ming Univ, Fac Med, Sch Med, Taipei, Taiwan

[3] Natl Cheng Kung Univ Hosp, Dept Internal Med, Tainan, Taiwan

[4] Natl Taiwan Univ Hosp, Div Infect Dis, Taipei, Taiwan

[5] Natl Taiwan Univ, Coll Med, Taipei, Taiwan

[6] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Coll Med, Dept Pediat, Taipei, Taiwan

[7] Changhua Christian Hosp, Dept Internal Med, Div Infect Dis, Changhua, Taiwan

[8] Chi Mei Med Ctr, Div Infect Dis, Tainan, Taiwan

[9] China Med Univ, Childrens Hosp, Div Pediat Infect Dis, Taichung, Taiwan

[10] Triserv Gen Hosp, Natl Def Med Ctr, Dept Internal Med, Div Infect Dis & Trop Med, Taipei, Taiwan

[11] Chang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Internal Med, Div Infect Dis,Coll Med, Taoyuan, Taiwan

[12] Kaohsiung Vet Gen Hosp, Dept Pediat, Kaohsiung, Taiwan

[13] Shin Kong Wu Ho Su Mem Hosp, Dept Internal Med, Div Gen Med, Infect Dis, Taipei, Taiwan

[14] Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Internal Med, Div Infect Dis, Kaohsiung, Taiwan

[15] Chang Gung Univ, Chang Gung Childrens Hosp, Chang Gung Mem Hosp, Dept Pediat,Coll Med, Taoyuan, Taiwan

[16] Taipei Vet Gen Hosp, Dept Internal Med, Div Gen Med, Infect Dis, Taipei, Taiwan

[17] Kaohsiung Chang Gung Mem Hosp, Dept Internal Med, Div Infect Dis, Kaohsiung, Taiwan

[18] Kaohsiung Vet Gen Hosp, Dept Med Educ & Res, Kaohsiung, Taiwan

[19] Kaohsiung Med Univ, Sch Pharm, Dept Pharm, Kaohsiung, Taiwan

[20] Kaohsiung Vet Gen Hosp, Dept Pharm, Kaohsiung, Taiwan

[21] Taipei Med Univ, Div Infect Dis, Shuang Ho Hosp, Taipei, Taiwan

来源：

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION | 2020年 / 53卷 / 02期

关键词：

Clostridium difficile; Diarrhea; CDI; Infectious diarrhea; FECAL MICROBIOTA TRANSPLANTATION; VANCOMYCIN-RESISTANT ENTEROCOCCI; CLINICAL-PRACTICE GUIDELINES; HEALTH-CARE EPIDEMIOLOGY; PROTON PUMP INHIBITORS; ORAL VANCOMYCIN; RISK-FACTORS; SOUTHERN TAIWAN; 1ST RECURRENCE; MEDICAL-CENTER;

D O I：

10.1016/j.jmii.2020.02.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Clostridioides difficile infection (CDI) is a major enteric disease associated with antibiotic use and a leading cause of hospital-acquired infections worldwide. This is the first guideline for treatment of CDI in Taiwan, aiming to optimize medical care for patients with CDI. The target audience of this document includes all healthcare personnel who are involved in the medical care of patients with CDI. The 2018 Guidelines Recommendations for Evidence-based Antimicrobial agents use in Taiwan (GREAT) working group was formed, comprising of infectious disease specialists from 13 medical centers in Taiwan, to review the evidence and draft recommendations using the grading of recommendations assessment, development, and evaluation (GRADE) methodology. A nationwide expert panel reviewed the recommendations during a consensus meeting in March 2019. The recommendation is endorsed by the Infectious Diseases Society of Taiwan (IDST). This guideline describes the epidemiology and risk factors of CDI, and provides recommendations for treatment of CDI in both adults and children. Recommendations for treatment of the first episode of CDI, first recurrence, second and subsequent recurrences of CDI, severe CDI, fulminant CDI, and pediatric CDI are provided. Copyright (C) 2020, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC.

引用

页码：191 / 208

页数：18

共 131 条

[1] Risk Factors for Recurrence, Complications and Mortality in Clostridium difficile Infection: A Systematic Review [J].