Serum and Urine Levels of Vascular Endothelial Growth Factor as Prognostic Markers in Patients with Bladder Cancer

被引：0

作者：

Ayati, Mohsen ^{[1
]}

Ghorani, Hossein ^{[1
]}

Amini, Erfan ^{[1
]}

Nowroozi, Mohammad Reza ^{[1
]}

Jamshidian, Hassan ^{[1
]}

Moghadam, Solmaz Ohadian ^{[1
]}

机构：

[1] Univ Tehran Med Sci, Urooncol Res Ctr, Tehran, Iran

来源：

MIDDLE EAST JOURNAL OF CANCER | 2020年 / 11卷 / 02期

关键词：

Vascular endothelial growth factor (VEGF); Bladder cancer; Tumor marker; TRANSITIONAL-CELL CARCINOMA; LYMPH-NODE METASTASIS; FACTOR EXPRESSION; ANGIOGENESIS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Bladder cancer is the second most common urinary cancer after prostate cancer. Recent studies have shown higher serum and urinary vascular endothelial growth factor (VEGF) in increased angiogenesis. In this study, the mean serum and urine level of VEGF was assessed in patients with bladder cancer. Methods: In this case-control study, 46 patients with bladder cancer referred to Imam-Khomeini Hospital in Tehran, Iran and 38 subjects as control, were enrolled and the mean serum and urine level of VEGF was assessed and compared between the groups. Results: The mean serum level of VEGF was 478.7, 518.4, and 648.1 in control, low-grade, and high-grade groups, respectively, with no significant difference (P=0.175). The mean urine level of VEGF was 414.2, 968.3, and 848.4 in control, low-grade, and high-grade groups, respectively, with significant difference (P=0.010). Conclusion: The mean urine level of VEGF in patients with bladder cancer is higher than healthy subjects.

引用

页码：198 / 202

页数：5

共 27 条

[1] Serum levels of vascular endothelial growth factor as a prognostic factor in bladder cancer [J].