Essential advances in surgical and adjuvant therapies for colorectal cancer 2018-2019

被引：27

作者：

Akagi, Tomonori ^{[1
]}

Inomata, Masafumi ^{[1
]}

机构：

[1] Oita Univ, Fac Med, Dept Gastroenterol & Pediat Surg, 1-1 Idaigaoka,Hasama Machi, Yufu City, Oita 8795593, Japan

来源：

ANNALS OF GASTROENTEROLOGICAL SURGERY | 2020年 / 4卷 / 01期

关键词：

adjuvant chemotherapy; colorectal cancer; surgical treatment; TOTAL MESORECTAL EXCISION; SHORT-TERM OUTCOMES; LOW-RECTAL-CANCER; III COLON-CANCER; LAPAROSCOPIC-ASSISTED RESECTION; RANDOMIZED PHASE-III; TEGAFUR PLUS LEUCOVORIN; MRC CLASICC TRIAL; OPEN SURGERY; STAGE-II;

D O I：

10.1002/ags3.12307

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Surgical resection and adjuvant chemotherapy are the only treatment modalities for localized colorectal cancer that can obtain a "cure." The goal in surgically treating primary colorectal cancer is complete tumor removal along with dissection of systematic D3 lymph nodes. Adjuvant treatment controls recurrence and improves the prognosis of patients after they undergo R0 resection. Various clinical studies have promoted the gradual spread and clinical use of new surgical approaches such as laparoscopic surgery, robotic surgery, and transanal total mesorectal excision (TaTME). Additionally, the significance of adjuvant chemotherapy has been established and it is now recommended in the JSCCR (the Japanese Society for Cancer of the Colon and Rectum) guideline as a standard treatment. Herein, we review and summarize current surgical treatment and adjuvant chemotherapy for localized colorectal cancer and discuss recent advances in personalized medicine related to adjuvant chemotherapy.

引用

页码：39 / 46

页数：8

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