Obstructive sleep apnea: A canonical correlation of cephalometric and selected demographic variables in obese and nonobese patients

被引:0
作者
Tangugsorn, V
Krogstad, O
Espeland, L
Lyberg, T
机构
[1] Univ Oslo, Inst Clin Dent, Dept Orthodont, Postgrad Program, N-0317 Oslo, Norway
[2] Univ Oslo, Ullevaal Univ Hosp, Res Forum, N-0317 Oslo, Norway
关键词
obstructive sleep apnea; obesity; cephalometric analysis; multivariate analyses;
D O I
暂无
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
One hundred male obstructive sleep apnea (OSA) patients were classified into 2 groups on the basis of body mass index (BMI): 43 nonobese (BMI < 30 kg/m(2)) and 57 obese (BMI <greater than or equal to> 30 kg/m(2)) patients. A comprehensive cephalometric analysis with a multivariate statistical method was performed in order to define the different principal components (PCs) of cervico-craniofacial skeletal and upper airway soft tissue morphology in each group and how they contributed to selected elements of the patient demographic data, ie, apnea-hypopnea index (AHI), nocturnal oxyhemoglobin saturation, and BMI. Thirty cephalometric variables of cervico-craniofacial skeletal morphology were reduced to 8 PCs describing 84.4% and 85.4% of the total variance in obese and nonobese OSA patients, respectively. Sixteen cephalometric variables of hyoid bone position and head posture were reduced to 4 PCs describing 84.4% and 85.9% of the total variance in obese and nonobese OSA patients, respectively. Twenty cephalometric variables of upper airway soft tissue morphology were reduced to 7 PCs describing 89.5% and 84.6% of the total variance in obese and nonobese OSA patients, respectively. For further analysis of PCs, a stepwise multiple regression analysis was chosen. Two dependent variables of interest are the minimal distance of the posterior pharyngeal airway space (PASmin) and AHI. PASmin accounted for 95.3% (obese OSA group) and 74.3% (nonobese OSA group) with 7 PCs and AHI for 46% with 3 PCs in both groups. Three canonical variables and their correspondents with different loadings were established differently for both OSA groups, A canonical correlation successfully clarified the complexity of simultaneous relationship of the relevant variables. These analyses are proved useful to demonstrate the relationship of cervico-craniofacial skeletal and upper airway soft tissue morphology and selected demographic data. This lays down a basis for understanding the complicated pathogenic components of obese and nonobese OSA patients.
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页码:23 / 35
页数:13
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