Enantioseparation by chromatographic and electromigration techniques using ligand-exchange as chiral separation principle

被引：63

作者：

Schmid, Martin G. ^{[1
]}

Guebitz, Gerald ^{[1
]}

机构：

[1] Karl Franzens Univ Graz, Inst Pharmaceut Sci, Dept Pharmaceut Chem, A-8010 Graz, Austria

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2011年 / 400卷 / 08期

关键词：

Ligand-exchange; Chiral selectors; Chemically bonded phases; Dynamically coated phases; Monolithic phases; HPLC; Capillary electrophoresis; Capillary electrochromatography; AMINO-ACID ENANTIOMERS; MONOLITHIC SILICA COLUMN; ALPHA-HYDROXY ACIDS; SOL-GEL PROCESS; CAPILLARY-ELECTROPHORESIS; OPTICAL ISOMERS; CONTINUOUS BEDS; LIQUID-CHROMATOGRAPHY; CU(II) COMPLEXES; BORATE ANION;

D O I：

10.1007/s00216-011-4737-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This article gives a short overview of the application of the principle of chiral ligand-exchange in HPLC, CE, and CEC. Since its introduction by Davankov, more than thousand articles have appeared in this field. Citing all these papers would extend the scope of this review-it would fill several books. Therefore only some milestones are mentioned in this article and it will focus on our own activities in this field. Some new developments are mentioned, and selected biochemical and biomedical application are presented.

引用

页码：2305 / 2316

页数：12

共 50 条

[21] Mechanistic Aspects and Applications of Chiral Ligand-Exchange Chromatography [J].

Natalini, Benedetto ;

Sardella, Roccaldo ;

Macchiarulo, Antonio ;

Marinozzi, Maura ;

Camaioni, Emidio ;

Pellicciari, Roberto .

ADVANCES IN CHROMATOGRAPHY, VOL 49, 2011, 49 :71-134

[22] Chiral separation and analysis of antifungal drugs by chromatographic and electromigration techniques: Results achieved in 2010-2020 [J].

D'Orazio, Giovanni ;

Fanali, Chiara ;

Dal Bosco, Chiara ;

Gentili, Alessandra ;

Fanali, Salvatore .

REVIEWS IN ANALYTICAL CHEMISTRY, 2021, 40 (01) :220-252

[23] Recent advances in chiral separation of amino acids using capillary electromigration techniques [J].

Giuffrida, Alessandro ;

Maccarrone, Giuseppe ;

Cucinotta, Vincenzo ;

Orlandini, Serena ;

Contino, Annalinda .

JOURNAL OF CHROMATOGRAPHY A, 2014, 1363 :41-50

[24] Enantioseparation by ligand-exchange using particle-loaded monoliths:: Capillary-LC versus capillary electrochromatography [J].

Schmid, Martin G. ;

Koidl, Julia ;

Wank, Pamela ;

Kargl, Gabriele ;

Zoehrer, Helga ;

Guebitz, Gerald .

JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS, 2007, 70 (01) :77-85

[25] Separation of Tryptophan Enantiomers by Ligand-Exchange Chromatography With Novel Chiral Ionic Liquids Ligand [J].

Qing, Haiqun ;

Jiang, Xinyu ;

Yu, Jingang .

CHIRALITY, 2014, 26 (03) :160-165

[26] SYNTHESIS OF CHIRAL LIGAND-EXCHANGE RESIN [J].

HE, BL ;

YAN, HS ;

YU, K ;

CHENG, XH ;

NI, AG .

CHINESE SCIENCE BULLETIN, 1993, 38 (17) :1451-1454

[27] The study of solution equilibria in chiral capillary electrophoresis by the ligand-exchange mechanism [J].

Maccarrone, Giuseppe ;

Contino, Annalinda ;

Cucinotta, Vincenzo .

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2012, 32 :133-153

[28] Chiral separation and determination of ofloxacin enantiomers by ionic liquid-assisted ligand-exchange chromatography [J].

Bi, Wentao ;

Tian, Minglei ;

Row, Kyung Ho .

ANALYST, 2011, 136 (02) :379-387

[29] Role of the charge in continuous beds in the chiral separation of hydroxy acids by ligand-exchange capillary electrochromatography [J].

Lecnik, O ;

Gübitz, G ;

Schmid, MG .

ELECTROPHORESIS, 2003, 24 (17) :2983-2985

[30] Cyclopropyl-Containing Sulfonyl Amino Acids: Exploring the Enantioseparation Through Chiral Ligand-Exchange Chromatography [J].

Sardella, R. ;

Ianni, F. ;

Pucciarini, L. ;

Marinozzi, M. ;

Zlotskii, S. S. ;

Natalini, B. .

RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2017, 87 (05) :1079-1084

← 1 2 3 4 5 →