Elective neck dissection in salivary gland malignancies: Systematic review and meta-analysis

被引：16
作者：
Yan, Flora [1 ]
Lao, Wilson P. [2 ]
Nguyen, Shaun A. [3 ]
Sharma, Anand K. [4 ]
Day, Terry A. [3 ]
机构：
[1] Temple Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Philadelphia, PA 19122 USA
[2] Loma Linda Univ Hlth, Dept Otolaryngol Head & Neck Surg, Loma Linda, CA USA
[3] Med Univ South Carolina, Head & Neck Tumor Ctr, Dept Otolaryngol Head & Neck Surg, Charleston, SC 29425 USA
[4] Med Univ South Carolina, Dept Radiat Oncol, Charleston, SC 29425 USA
来源：
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2022年 / 44卷 / 02期
关键词：
elective neck dissection; occult nodal metastasis; parotid cancer; salivary gland cancer; salivary gland malignancy; ADENOID CYSTIC CARCINOMA; LYMPH-NODE METASTASIS; PAROTID-GLAND; RISK-FACTORS; PROGNOSTIC-FACTORS; MANAGEMENT; PATTERNS; OUTCOMES; HEAD; CANCER;
D O I：
10.1002/hed.26923
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
We defined the occult nodal metastasis (ONM) rate of clinical node-negative salivary gland malignancies and examined the role of elective neck dissection (END). Meta-analysis querying four databases, from inception of databases to March 25th, 2020. Fifty-one studies with 11 698 patients were included. ONM rates were 64% for salivary ductal carcinoma (SDC), 51% for undifferentiated carcinoma, 34% for carcinoma ex-pleomorphic adenoma (CXPA), 32% for adenocarcinoma not otherwise specified (ANOS), 31% for lymphoepithelial carcinoma (LE), 20% for mucoepidermoid carcinoma, 17% for acinic cell carcinoma, and 17% for adenoid cystic carcinoma. T3/T4 tumors had a 2.3 times increased risk of ONM than T1/T2 tumors. High-grade tumors had a 3.8 times increased risk of ONM than low/intermediate-grade tumors. ONM rates were exceedingly high for T3/T4, high-grade, and undifferentiated, SDC, ANOS, CXPA, and LE tumors, indicating the potential role of END.
引用
收藏
页码：505 / 517
页数：13
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