Orthostatic Hypotension and Albuminocytologic Dissociation as Primary Manifestations of the Paraneoplastic Syndrome

被引：1
作者：
Li, Jingjing [1 ,2 ]
Li, Yi [3 ]
Xing, Shihui [1 ,2 ]
Zhang, Jian [1 ,2 ]
Qiu, Baoshan [1 ,2 ]
Zeng, Jinsheng [1 ,2 ]
Fan, Yuhua [1 ,2 ]
机构：
[1] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Neurol, Zhongshan Rd 2, Guangzhou 510080, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Affiliated Hosp 1, Stroke Ctr, Zhongshan Rd 2, Guangzhou 510080, Guangdong, Peoples R China
[3] Jinan Univ, Coll Med, Guangzhou Red Cross Hosp, Dept Neurol, Guangzhou, Guangdong, Peoples R China
来源：
EUROPEAN NEUROLOGY | 2018年 / 80卷 / 1-2期
基金：
国家重点研发计划;
关键词：
Orthostatic hypotension; Paraneoplastic syndrome; Autonomic dysfunction; Albuminocytologic dissociation;
D O I：
10.1159/000493865
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background: Orthostatic hypotension (OH) is the key manifestation of autonomic dysfunction with many causes. Systemic neurological causes such as paraneoplastic syndrome are usually ignored. Methods: We retrospectively analyzed clinical and examination data of 2 patients who were hospitalized, with onset symptom of OH and who were diagnosed as paraneoplastic syndrome. Results: The patients were characteristic of an initial symptom of OH, positive anti-Hu antibody and albuminocytologic dissociation in the cerebrospinal fluid. Patient 2 died and Patient 1 worsened during follow-up. Conclusions: The diagnosis of paraneoplastic syndrome is usually neglected when the onset symptoms are autonomic dysfunctions such as OH. Neurologists should improve their knowledge to diagnose accurately.
引用
收藏
页码：78 / 81
页数：4
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