Vaccines and Inflammatory Bowel Disease

被引：16

作者：

Kotton, Camille Nelson ^{[1
,2
]}

机构：

[1] Massachusetts Gen Hosp, Div Infect Dis, Transplant Infect Dis & Compromised Host Program, Boston, MA 02114 USA

[2] Harvard Univ, Sch Med, Dept Med, Boston, MA USA

来源：

DIGESTIVE DISEASES | 2010年 / 28卷 / 03期

关键词：

Immunosuppression; Inflammatory bowel disease; Vaccine; DISSEMINATED PRIMARY VARICELLA; HERPES-ZOSTER; CROHNS-DISEASE; RISK-FACTORS; HEPATITIS-B; OPPORTUNISTIC INFECTIONS; ULCERATIVE-COLITIS; INFLUENZA VACCINE; SPLENIC FUNCTION; IMMUNE-RESPONSE;

D O I：

10.1159/000320412

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, are at increased risk for infection due to both their underlying disease and the immunosuppressive therapy used to treat the disease. Numerous groups and papers support the routine vaccination of IBD patients, yet many opportunities to vaccinate this vulnerable population are missed. While immunogenicity may be somewhat attenuated, some protection is likely to be provided, especially when vaccination is performed during periods of reduced immunosuppression. Live viral vaccines should be avoided during periods of more intense immunosuppression; further specific guidance on this as well as information on individual vaccines is provided. Copyright (C) 2010 S. Karger AG, Basel

引用

页码：525 / 535

页数：11

共 60 条

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