A young female patient with an androgen-secreting tumor:: A rare malignant disease

被引:3
作者
Bozbora, A [1 ]
Erbil, Y
Özbey, N
Kapran, Y
Özarmagan, S
Berber, E
Molvalilar, S
机构
[1] Istanbul Univ, Fac Med, Dept Gen Surg, Div Endocrinol, Istanbul, Turkey
[2] Istanbul Univ, Fac Med, Dept Internal Med, Div Endocrinol Metab & Nutr, Istanbul, Turkey
[3] Istanbul Univ, Fac Med, Dept Pathol, Istanbul, Turkey
关键词
adrenal carcinoma; hirsutism; androgen-secreting tumors;
D O I
10.1177/030089160008600612
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A 23-year-old female patient presented with hirsutism and fatigue nine months after delivery, Endocrine assessment showed high testesterone, DHEA-S and androstenedione levels. Abdominal computed tomography and ultrasonography revealed the presence of a large tumor in the right renal region. Right adrenalectomy was performed resulting in a diagnosis of a functional adrenal tumor. Pathological examination showed a steroidogenically active tumor. Adjuvant chemotheraphy was administered postoperatively, At three months following surgery all endocrinological tests normalized, but river metastases were detected by abdominal CT, Eight months after the operation the patient died of hepatic and renal failure, Androgen-secreting adrenal tumors are seen Very rarely yet the prognosis is poor due to their agressive nature.
引用
收藏
页码:487 / 488
页数:2
相关论文
共 9 条
[1]  
CONRAD DV, 1995, AM J GYNECOL, V175, P1912
[2]   An unusual case of bilateral virilizing adrenal adenoma co-secreting androgens and cortisol [J].
Delgrange, E ;
Goethals, P ;
Laka, A ;
Maiter, D ;
Lambert, M .
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1996, 19 (06) :377-381
[3]   IDENTIFICATION OF VIRILIZING ADRENAL-TUMORS IN HIRSUTE WOMEN [J].
DERKSEN, J ;
NAGESSER, SK ;
MEINDERS, AE ;
HAAK, HR ;
VANDEVELDE, CJH .
NEW ENGLAND JOURNAL OF MEDICINE, 1994, 331 (15) :968-973
[4]  
HAMILTONFORLEY D, 1997, CLIN ENDOCRINE ONCOL, P323
[5]   STEROIDOGENESIS IN AN ESTROGEN-PRODUCING ADRENAL-TUMOR IN A YOUNG WOMAN - COMPARISON WITH STEROID PROFILES ASSOCIATED WITH CORTISOL-PRODUCING AND ANDROGEN-PRODUCING TUMORS [J].
MCKENNA, TJ ;
OCONNELL, Y ;
CUNNINGHAM, S ;
MCCABE, M ;
CULLITON, M .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1990, 70 (01) :28-34
[6]  
ORTH D, 1992, WILLIAMS TXB ENDOCRI, P517
[7]  
ROSS NS, 1990, NEW ENGL J MED, V323, P1401
[8]  
WOOTEN MD, 1993, CANCER, V72, P3145, DOI 10.1002/1097-0142(19931201)72:11<3145::AID-CNCR2820721105>3.0.CO
[9]  
2-N