The genetics, biosynthesis and regulation of toxic specialized metabolites of cyanobacteria

被引：96
作者：
Pearson, Leanne A. [1 ]
Dittmann, Elke [2 ]
Mazmouz, Rabia [1 ]
Ongley, Sarah E. [1 ]
D'Agostino, Paul M. [1 ]
Neilan, Brett A. [1 ]
机构：
[1] Univ New S Wales, Biotechnol & Biomol Sci, Sydney, NSW 2052, Australia
[2] Univ Potsdam, Inst Biochem & Biol, Mikrobiol, D-14476 Golm, Germany
来源：
HARMFUL ALGAE | 2016年 / 54卷
关键词：
Cyanobacteria; Cyanotoxins; Specialized metabolites; Genetics; Biosynthesis; Regulation; ANABAENA-FLOS-AQUAE; CYLINDROSPERMOPSIS-RACIBORSKII NOSTOCALES; WATER BENTHIC CYANOBACTERIUM; SHELLFISH POISONING TOXINS; MICROCYSTIN-LR SYNTHESIS; METHYLAMINO-L-ALANINE; ANATOXIN-A; 1ST REPORT; SAXITOXIN PRODUCTION; LYNGBYA-MAJUSCULA;
D O I：
10.1016/j.hal.2015.11.002
中图分类号：
Q17 [水生生物学];
学科分类号：
071004 ;
摘要：
The production of toxic metabolites by cyanobacterial blooms represents a significant threat to the health of humans and ecosystems worldwide. Here we summarize the current state of the knowledge regarding the genetics, biosynthesis and regulation of well-characterized cyanotoxins, including the microcystins, nodularin, cylindrospermopsin, saxitoxins and antitoxins, as well as the lesser-known marine toxins (e.g. lyngbyatoxin, aplysiatoxin, jamaicamides, barbamide, curacin, hectochlorin and apratoxins). (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码：98 / 111
页数：14
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