Time-resolved photon emission from layered turbid media

被引:78
作者
Hielscher, AH
Liu, HL
Chance, B
Tittel, FK
Jacques, SL
机构
[1] RICE UNIV,DEPT ELECT & COMP ENGN,HOUSTON,TX 77251
[2] UNIV PENN,DEPT BIOCHEM & BIOPHYS,PHILADELPHIA,PA 19104
[3] UNIV TEXAS,MD ANDERSON CANCER CTR,LASER BIOL RES LAB,HOUSTON,TX 77030
来源
APPLIED OPTICS | 1996年 / 35卷 / 04期
关键词
diffusion theory; photon migration; scattering; time-resolved; photon counting; reflectance; multilayer; Monte Carlo simulation; tissue phantom; blood oxygenation; brain;
D O I
10.1364/AO.35.000719
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We present numerical and experimental results of time-resolved emission profiles from various layered turbid media. Numerical solutions determined by time-resolved Monte Carlo simulations are compared with measurements on layered-tissue phantoms made from gelatin. In particular, we show that in certain cases the effects of the upper layers can be eliminated. As a practical example, these results are used to analyze in vivo measurements on the human head. This demonstrates the influence of skin, skull, and meninges on the determination of the blood oxygenation in the brain. (C) 1996 Optical Society of America
引用
收藏
页码:719 / 728
页数:10
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