Plain Silver Surface Plasmon Resonance for Microarray Application

被引:40
作者
Cheng, Zhiqiang [1 ,2 ]
Wang, Zhiyou [1 ]
Gillespie, Doreen E. [3 ]
Lausted, Christopher [4 ]
Zheng, Zheng [5 ]
Yang, Mo [1 ]
Zhu, Jinsong
机构
[1] Natl Ctr NanoSci & Technol, Beijing 100190, Peoples R China
[2] Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China
[3] Plexera LLC, Woodinville, WA 98072 USA
[4] Inst Syst Biol, Seattle, WA 98103 USA
[5] Beihang Univ, Sch Elect & Informat Engn, Beijing 100191, Peoples R China
关键词
SELF-ASSEMBLED MONOLAYERS; GOLD SURFACES; FILM; ENHANCEMENT; SENSITIVITY; STABILITY; SENSORS; SPECTROSCOPY; MICROSCOPY; BIOSENSOR;
D O I
10.1021/ac504110t
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The application scope of surface plasmon resonance (SPR) and SPR imaging (SPRi) is rapidly growing, and tools such as high-performance and low-cost slides could enable more rapid growth of the field. We describe herein a novel silver slide, addressing the inherent instability of plain silver structure by improving adhesion between the glass substrate and the silver layer with a thin buffer layer of gold. Covered by a self-assembled monolayer (SAM) only, SPR characteristics of the slide remain steady for more than 3 months under regular storage. In a bioassay, the slide substantiates the predicted nearly 100% sensitivity improvement over gold slides and exhibits exceptional performance stability as determined by sensitivity and resolution measurements during the extended 40?000 s multicycle experiment. We demonstrate the suitability of this new slide for large-area SPRi, describing analysis results from a 1?296-ligand protein microarray. We predict this slide structure will provide a stable, high-sensitivity solution for high-throughput SPRi applications and other surface analysis platforms.
引用
收藏
页码:1466 / 1469
页数:4
相关论文
共 32 条
[1]  
Bruijin H. E., 1992, APPL OPTICS, V31, P440
[2]   SPR microscopy and its applications to high-throughput analyses of biomolecular binding events and their kinetics [J].
Campbell, Charles T. ;
Kim, Gibum .
BIOMATERIALS, 2007, 28 (15) :2380-2392
[3]   Effect of aging on optical properties of bimetallic sensor chips [J].
Chen, X. ;
Jiang, K. .
OPTICS EXPRESS, 2010, 18 (02) :1105-1112
[4]   Compact, high performance surface plasmon resonance imaging system [J].
Chinowsky, Timothy M. ;
Grow, Michael S. ;
Johnston, Kyle S. ;
Nelson, Kjell ;
Edwards, Thayne ;
Fu, Elain ;
Yager, Paul .
BIOSENSORS & BIOELECTRONICS, 2007, 22 (9-10) :2208-2215
[5]   Highly Stable Silver Nanoplates for Surface Plasmon Resonance Biosensing [J].
Gao, Chuanbo ;
Lu, Zhenda ;
Liu, Ying ;
Zhang, Qiao ;
Chi, Miaofang ;
Cheng, Quan ;
Yin, Yadong .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (23) :5629-5633
[6]   Surface plasmon resonance sensors: review [J].
Homola, J ;
Yee, SS ;
Gauglitz, G .
SENSORS AND ACTUATORS B-CHEMICAL, 1999, 54 (1-2) :3-15
[7]   Surface plasmon resonance sensors for detection of chemical and biological species [J].
Homola, Jiri .
CHEMICAL REVIEWS, 2008, 108 (02) :462-493
[8]   Imaging surface plasmon resonance sensor based on multiple wavelengths:: Sensitivity considerations [J].
Johansen, K ;
Arwin, H ;
Lundström, I ;
Liedberg, B .
REVIEW OF SCIENTIFIC INSTRUMENTS, 2000, 71 (09) :3530-3538
[9]   Two-Photon Excited Fluorescence Enhancement for Ultrasensitive DNA Detection on Large-Area Gold Nanopatterns [J].
Jung, Jin-Mi ;
Yoo, Hae-Wook ;
Stellacci, Francesco ;
Jung, Hee-Tae .
ADVANCED MATERIALS, 2010, 22 (23) :2542-2546
[10]   Quantitative Serum Proteomics from Surface Plasmon Resonance Imaging [J].
Lausted, Christopher ;
Hu, Zhiyuan ;
Hood, Leroy .
MOLECULAR & CELLULAR PROTEOMICS, 2008, 7 (12) :2464-2474