Methotrexate and glucocorticoids, but not anticytokine therapy, impair the immunogenicity of a single dose of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic inflammatory arthritis

被引:40
作者
Bugatti, Serena [1 ,2 ]
De Stefano, Ludovico [1 ,2 ]
Balduzzi, Silvia [1 ]
Greco, Maria Immacolata [1 ]
Luvaro, Terenzj [1 ]
Cassaniti, Irene
Bogliolo, Laura [1 ]
Mazzucchelli, Iolanda [2 ]
D'Onofrio, Bernardo [1 ,2 ]
di Lernia, Michele [1 ]
Mauric, Eleonora [1 ,2 ]
Lilleri, Daniele [3 ]
Baldanti, Fausto [3 ,4 ]
Manzo, Antonio [1 ,2 ]
Montecucco, Carlomaurizio [1 ,2 ]
机构
[1] Fdn IRCCS Policlin San Matteo, Div Rheumatol, I-27100 Pavia, Italy
[2] Univ Pavia, Dept Internal Med & Therapeut, Pavia, Italy
[3] Fdn IRCCS Policlin San Matteo, Microbiol & Virol Dept, Pavia, Italy
[4] Univ Pavia, Dept Clin Surg Diagnost & Paediat Sci, Pavia, Italy
关键词
COVID-19; vaccination; methotrexate; biological therapy; glucocorticoids;
D O I
10.1136/annrheumdis-2021-220862
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1635 / 1638
页数:4
相关论文
共 6 条
[1]   Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients [J].
Boyarsky, Brian J. ;
Werbel, William A. ;
Avery, Robin K. ;
Tobian, Aaron A. R. ;
Massie, Allan B. ;
Segev, Dorry L. ;
Garonzik-Wang, Jacqueline M. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2021, 325 (17) :1784-1786
[2]   Testing mobile air purifiers in a school classroom: Reducing the airborne transmission risk for SARS-CoV-2 [J].
Curtius, J. ;
Granzin, M. ;
Schrod, J. .
AEROSOL SCIENCE AND TECHNOLOGY, 2021, 55 (05) :586-599
[3]   Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study [J].
Monin, Leticia ;
Laing, Adam G. ;
Munoz-Ruiz, Miguel ;
McKenzie, Duncan R. ;
Del Barrio, Irene Del Molino ;
Alaguthurai, Thanussuyah ;
Domingo-Vila, Clara ;
Hayday, Thomas S. ;
Graham, Carl ;
Seow, Jeffrey ;
Abdul-Jawad, Sultan ;
Kamdar, Shraddha ;
Harvey-Jones, Elizabeth ;
Graham, Rosalind ;
Cooper, Jack ;
Khan, Muhammad ;
Vidler, Jennifer ;
Kakkassery, Helen ;
Sinha, Shubhankar ;
Davis, Richard ;
Dupont, Liane ;
Quijorna, Isaac Francos ;
O'Brien-Gore, Charlotte ;
Lee, Puay Ling ;
Eum, Josephine ;
Poole, Maria Conde ;
Joseph, Magdalene ;
Davies, Daniel ;
Wu, Yin ;
Swampillai, Angela ;
North, Bernard, V ;
Montes, Ana ;
Harries, Mark ;
Rigg, Anne ;
Spicer, James ;
Malim, Michael H. ;
Fields, Paul ;
Patten, Piers ;
Di Rosa, Francesca ;
Papa, Sophie ;
Tree, Timothy ;
Doores, Katie J. ;
Hayday, Adrian C. ;
Irshad, Sheeba .
LANCET ONCOLOGY, 2021, 22 (06) :765-778
[4]   SARS-CoV-2 vaccination responses in untreated, conventionally treated and anticytokine-treated patients with immune-mediated inflammatory diseases [J].
Simon, David ;
Tascilar, Koray ;
Fagni, Filippo ;
Kroenke, Gerhard ;
Kleyer, Arnd ;
Meder, Christine ;
Atreya, Raja ;
Leppkes, Moritz ;
Kremer, Andreas E. ;
Ramming, Andreas ;
Pachowsky, Milena L. ;
Schuch, Florian ;
Ronneberger, Monika ;
Kleinert, Stefan ;
Hueber, Axel J. ;
Manger, Karin ;
Manger, Bernhard ;
Berking, Carola ;
Sticherling, Michael ;
Neurath, Markus F. ;
Schett, Georg .
ANNALS OF THE RHEUMATIC DISEASES, 2021, 80 (10) :1312-1316
[5]   Rituximab, but not other antirheumatic therapies, is associated with impaired serological response to SARS-CoV-2 vaccination in patients with rheumatic diseases [J].
Spiera, Robert ;
Jinich, Sarah ;
Jannat-Khah, Deanna .
ANNALS OF THE RHEUMATIC DISEASES, 2021, 80 (10) :1357-+
[6]   Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates [J].
Walsh, Edward E. ;
Frenck, Robert W., Jr. ;
Falsey, Ann R. ;
Kitchin, Nicholas ;
Absalon, Judith ;
Gurtman, Alejandra ;
Lockhart, Stephen ;
Neuzil, Kathleen ;
Mulligan, Mark J. ;
Bailey, Ruth ;
Swanson, Kena A. ;
Li, Ping ;
Koury, Kenneth ;
Kalina, Warren ;
Cooper, David ;
Fontes-Garfias, Camila ;
Shi, Pei-Yong ;
Tuereci, Oezlem ;
Tompkins, Kristin R. ;
Lyke, Kirsten E. ;
Raabe, Vanessa ;
Dormitzer, Philip R. ;
Jansen, Kathrin U. ;
Sahin, Ugur ;
Gruber, William C. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (25) :2439-2450