Understanding fatigue in adults with visual impairment: A path analysis study of sociodemographic, psychological and health-related factors

被引:13
作者
Schakel, Wouter [1 ]
Bode, Christina [2 ]
van de Ven, Peter M. [3 ]
van der Aa, Hilde P. A. [1 ]
Hulshof, Carel T. J. [4 ]
van Rens, Gerardus H. M. B. [1 ,5 ]
van Nispen, Ruth M. A. [1 ]
机构
[1] Vrije Univ Amsterdam, Amsterdam Publ Hlth Res Inst, Dept Ophthalmol, Amsterdam UMC, Amsterdam, Netherlands
[2] Univ Twente, Dept Psychol Hlth & Technol, Enschede, Netherlands
[3] Vrije Univ Amsterdam, Amsterdam Publ Hlth Res Inst, Dept Epidemiol & Biostat, Amsterdam UMC, Amsterdam, Netherlands
[4] Univ Amsterdam, NetherlandsCoronel Inst Occupat Hlth, Amsterdam Publ Hlth Res Inst, Amsterdam UMC, Amsterdam, Netherlands
[5] Elkerliek Hosp, Dept Ophthalmol, Helmond, Netherlands
关键词
QUALITY-OF-LIFE; MULTIPLE-SCLEROSIS; SLEEP DISTURBANCES; VISION; IMPACT; CANCER; DEPRESSION; DISORDERS; ASSOCIATION; DISABILITY;
D O I
10.1371/journal.pone.0224340
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Fatigue is a disabling problem in patients with visual impairment, but its etiology is still poorly understood. Our objective was to identify the determinants of fatigue in adults with visual impairment compared to adults with normal sight. Methods Cross-sectional data on fatigue and sociodemographic, psychological and health-related factors was obtained with validated questionnaires. Structural equational modeling using hypothesized relationships and explorative analyses were used to identify (in)direct pathways contributing to fatigue in 247 adults with visual impairment. The model was then tested in a reference group of 151 adults with normal sight. Results The final model explained 64% of fatigue variance in participants with visual impairment and revealed the following factors to be directly associated with fatigue: depressive symptoms (beta = 0.723, p< 0.001), perceived health (beta = -0.158, p = 0.004), accommodative coping (beta = 0.116, p = 0.030) and somatic comorbidity (beta = 0.311, p = 0.001). Self-efficacy demonstrated a beneficial indirect effect on fatigue (beta = -0.228, p< 0.001) mediated by depression, accommodative coping and perceived health. Sleep disorder had an indirect effect on fatigue (beta = 0.656, p< 0.001) mediated by depression and perceived health. After removal of sleep disorder, the model explained 58% of the fatigue variance in normally sighted adults but pathways involving accommodative coping and somatic comorbidity were not confirmed. Conclusions These findings suggest that depression and perceived health are important mediating factors that contribute to fatigue in persons with visual impairment and normal sight. In contrast, somatic comorbidity, sleep disorders and accommodative coping seem to have a specific contribution to vision-related fatigue. These factors should be addressed in interventions to assist individuals with visual impairment in dealing with fatigue.
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页数:18
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