MOBILITY OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS IN SOILS WITH AND WITHOUT AMENDMENT OF BIOSOLID

被引：8

作者：

Ascar, Loreto ^{[1
]}

Ahumada, Ines ^{[1
]}

Morales, Natalia ^{[1
]}

Garrido, Tatiana ^{[1
]}

Giordano, Ady ^{[2
]}

Karla Leiva, Y. ^{[1
]}

机构：

[1] Univ Chile, Fac Ciencias Quim & Farmaceut, Dept Quim Inorgan & Analit, Sergio Livingstone 1007,Casilla 233, Santiago, Chile

[2] Pontificia Univ Catolica Chile, Fac Quim, Dept Quim Inorgan, Av Vicuna Mackenna 4860,Casilla 306,Correo 22, Santiago, Chile

来源：

JOURNAL OF THE CHILEAN CHEMICAL SOCIETY | 2017年 / 62卷 / 03期

关键词：

Anti-inflammatory drugs; mobility; solid-phase extraction; HPLC-DAD; SOLID-PHASE EXTRACTION; LIQUID-CHROMATOGRAPHY; WASTE-WATER; PHARMACEUTICALS; SEWAGE; SLUDGE; WASTEWATERS; ESTROGENS; BEHAVIOR;

D O I：

10.4067/s0717-97072017000303593

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nonsteroidal anti-inflammatory drugs are widely used by humans as therapeutic agents to treat or prevent illnesses. Once ingested, part of them is excreted and enters the wastewater treatment plants generating biosolids that they may be used as fertilizing complements. The purpose of this study was to investigate the mobility of nonsteroidal anti-inflammatory drugs (ketoprofen, naproxen, diclofenac and ibuprofen) in soils and soils amended with biosolid. Studies of NSAIDs adsorption on two different soils were carried through batch equilibrium at room temperature. The mobility of NSAIDs in soils was studied through the use of leaching columns incorporating in the top section soil enriched with NSAIDs with and without biosolid. Ketoprofen, naproxen and ibuprofen were determined in the leaching columns. Anti-inflammatory mobility in the soil profile depends on the specific characteristics of each system soil-biosolid. In both soils there was little mobility of anti-inflammatory in the soil profile. In Linderos soil were found in greater quantity of Ibuprofen, naproxen and diclofenac that in Lonquen soil.

引用

页码：3593 / 3596

页数：4

共 24 条

[1] Nonsteroidal Anti-Inflammatory Drug Determination in Water Samples by HPLC-DAD under Isocratic Conditions [J].

Ascar, Loreto ;

Ahumada, Ines ;

Lopez, Alicia ;

Quintanilla, Francia ;

Leiva, Karla .

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2013, 24 (07) :1160-1166

[2] Combined microwave-assisted extraction and continuous solid-phase extraction prior to gas chromatography-mass spectrometry determination of pharmaceuticals, personal care products and hormones in soils, sediments and sludge [J].

Azzouz, Abdelmonaim ;

Ballesteros, Evaristo .

SCIENCE OF THE TOTAL ENVIRONMENT, 2012, 419 :208-215

[3] Appropriate use of non-steroidal anti-inflammatory drugs in rheumatology: guidelines from the Spanish Society of Rheumatology and the Mexican College of Rheumatology [J].

Bori Segura, Gerardo ;

Hernandez Cruz, Blanca ;

Gobbo, Milena ;

Lanas Arbeloa, Angel ;

Salazar Paramo, Mario ;

Teran Estrada, Leobardo ;

Diaz Gonzalez, Jose Federico ;

Espinosa Morales, Rolando ;

Galvan Villegas, Federico ;

Garcia Rodriguez, Luis Alberto ;

Alvaro-Gracia Alvaro, Jose Maria ;

Avila Armengol, Hilario ;

Carmona, Loreto ;

Rivera Redondo, Javier ;

Ventura Rios, Lucio .

REUMATOLOGIA CLINICA, 2009, 5 (01) :3-12

[4] Effects of pharmaceuticals present in aquatic environment on Phase I metabolism in fish [J].

Burkina, Viktoriia ;

Zlabek, Vladimir ;

Zamaratskaia, Galia .

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2015, 40 (02) :430-444

[5] Autoclaving kills soil microbes yet soil enzymes remain active [J].

Carter, David O. ;

Yellowlees, David ;

Tibbett, Mark .

PEDOBIOLOGIA, 2007, 51 (04) :295-299

[6] The presence of acidic and neutral drugs in treated sewage effluents and receiving waters in the Cornwallis and Annapolis River watersheds and the Mill CoveSewage Treatment Plant in Nova Scotia, Canada [J].

Crouse, Brian A. ;

Ghoshdastidar, Avik J. ;

Tong, Anthony Z. .

ENVIRONMENTAL RESEARCH, 2012, 112 :92-99

[7]

Darbar S. R., 2007, Caspian Journal of Environmental Sciences, V5, P87

[8] LC-MS2 trace analysis of antimicrobials in water, sediment and soil [J].

Díaz-Cruz, MS ;

Barceló, D .

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2005, 24 (07) :645-657

[9] STUDIES IN ADSORPTION .11. A SYSTEM OF CLASSIFICATION OF SOLUTION ADSORPTION ISOTHERMS, AND ITS USE IN DIAGNOSIS OF ADSORPTION MECHANISMS AND IN MEASUREMENT OF SPECIFIC SURFACE AREAS OF SOLIDS [J].

GILES, CH ;

MACEWAN, TH ;

NAKHWA, SN ;

SMITH, D .

JOURNAL OF THE CHEMICAL SOCIETY, 1960, (OCT) :3973-3993

[10] Trace determination of fluoroquinolone antibacterial agents in solid-phase extraction urban wastewater by and liquid chromatography with fluorescence detection [J].

Golet, EM ;

Alder, AC ;

Hartmann, A ;

Ternes, TA ;

Giger, W .

ANALYTICAL CHEMISTRY, 2001, 73 (15) :3632-3638

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