Selective flotation-spectrophotometric determination of trace copper(II) in natural waters, human blood and drug samples using phenanthraquinone monophenylthiosemicarbazone

被引：30

作者：

Khalifa, ME ^{[1
]}

Akl, MA ^{[1
]}

Ghazy, SES ^{[1
]}

机构：

[1] Mansoura Univ, Fac Sci, Dept Chem, Mansoura, Egypt

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2001年 / 49卷 / 06期

关键词：

copper; phenanthraquinone monophenylthiosemicarbazon; flotation; spectrophotometry; blood; complex and drug;

D O I：

10.1248/cpb.49.664

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Copper(ll) forms 1:1 and 1:2 intense red complexes with phenanthraquinone monophenylthiosemicarbazone (PPT) at pH 3-3.5 and greater than or equal to6.5, respectively, These complexes exhibit maximal absorbance at 545 and 517 nm, the molar absorptivity being 2.3 x 10(4) and 4.8 x 10(4) l mol(-1) cm(-1), respectively. However, the 1 : 1 complex was quantitatively Boated with oleic acid (HOL) surfactant in the pH range 4.5-5.5, providing a highly selective and sensitive procedure for the spectrophotometric determination of Cu-11, The molar absorptivity of the floated Cu-PPT complex was 1.5x10(5) l mol(-1) cm(-1). Beer's law was obeyed over the range 3-400 ppb at 545 nm, The analytical parameters affecting the flotation process and hence the determination of copper traces were reported. Also, the structure of the isolated solid complex and the mechanism of flotation were suggested. Moreover, the procedure H as successfully applied to the analysis of Cu-11 in natural waters, serum blood and some drug samples.

引用

页码：664 / 668

页数：5

共 24 条

[1]

ACKERMANN G, 1988, DETERMINATION TRACE, P49

[2] TRANSFORMATION OF SQUARE-PLANAR DSP2 CONFIGURATION OF NI(II) ALDOXIMATES INTO OCTAHEDRAL SP3D2 CONFIGURATION BY REACTION WITH TIN(IV) CHLORIDE [J].