AMPK and SNF1: Snuffing out stress

被引:34
|
作者
Hardie, D. Grahame [1 ]
机构
[1] Univ Dundee, Coll Life Sci, Div Mol Physiol, Dundee DD1 5EH, Scotland
关键词
ACTIVATED-PROTEIN-KINASE; ENERGY; YEAST; GAMMA-2-SUBUNIT; GLYCOGENOSIS; DEFICIENCY; MUTATION; BINDING; DISEASE; HEART;
D O I
10.1016/j.cmet.2007.10.001
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
AMP-activated protein kinase (AMPK) has attracted much attention for its key role in energy homeostasis. Three new papers providing structural information on mammalian and yeast AMPK homologs give insights into the binding of the regulatory nucleotides AMP and ATP and how mutations are associated with cardiac glycogen storage disorders.
引用
收藏
页码:339 / 340
页数:2
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