Unexpected Synthesis of N-Acyl Indolines via a Consecutive Cyclization of Iminophosphorane

被引：12
作者：
Li, Wen-Jing [1 ]
Zhao, Fen-Fen [1 ]
Ding, Ming-Wu [1 ]
机构：
[1] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China
来源：
SYNLETT | 2011年 / 02期
基金：
中国国家自然科学基金;
关键词：
N-acyl indoline; iminophosphorane; cyclization; Staudinger reaction; ENANTIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; INDOLES; ROUTE; AMINATION; STRATEGY;
D O I：
10.1055/s-0030-1259280
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
N-Acyl indolines were obtained unexpectedly from a consecutive cyclization of iminophosphorane in refluxing xylene or 1,2-dichlorobenzene in good yields. This new approach provides an efficient and direct access to the biologically important indolines which are further oxidizable to indoles and oxindoles.
引用
收藏
页码：265 / 267
页数：3
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