Direct coupling of nucleophiles with nitroaromatic compounds via fluoride-promoted oxidative nucleophilic aromatic substitution for hydrogen

被引:18
|
作者
Huertas, I [1 ]
Gallardo, I [1 ]
Marquet, J [1 ]
机构
[1] Univ Autonoma Barcelona, Dept Quim, E-08193 Barcelona, Spain
关键词
D O I
10.1016/S0040-4039(01)00485-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Useful yields are achieved in the regioselective direct coupling of amines, amides, and ketones with m-dinitrobenzene, 1-nitronaphthalene, and 1,3-dinitronaphthalene, through oxidatively activated nucleophilic aromatic substitution for hydrogen promoted by fluoride anions. (C) 2001 Elsevier Science Ltd. All rights reserved.
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页码:3439 / 3441
页数:3
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