Frequency of Bacteria Causing Neonatal Sepsis in Neonatal Intensive Care Unit

Objective: To determine the frequency of bacteria causing neonatal sepsis in Neonatal Intensive Unit (NICU). Study Design: Cross sectional descriptive study. Settings: Neonatal Intensive Care Unit, Department of Pediatrics Liaquat University of Medical and Health Sciences Hyderabad. Period: Six months from 8(th) July 2018 to 7(th) January 2019. Material and Methods: A total of 141 neonates with neonatal sepsis admitted in neonatal ICU were included in this study. The relevant clinical history and specific physical examination was performed by principal researcher. The blood cultures were obtained at the time of admission. The bacteriological profile was explored in pre-designed proforma. Results: The average age of the neonates were 18.33 +/- 6.93 days. There were 73 (51.77%) male and 68 (48.23%) female. Streptococcus pneumonia was the most common pathogens responsible for neonatal sepsis found in 33.3%, Escherichia coli (E. coli) was observed in 11.3%, Klebsiella 14.9%, Staphylococcus aureus (S. aureus) was 9.2%. Conclusion: We conclude that according to local patterns of bacterial pathogens Streptococcus pneumonia was the commonest pathogens followed by, E. coli, Klebsiella and S. aureus respectively.