A case of Aspergillus mediastinitis after heart transplantation successfully treated with liposomal amphotericin B, caspofungin and voriconazole

被引：25
作者：
Forestier, E
Remy, V
Lesens, O
Martinot, M
Hansman, Y
Eisenmann, B
Christmann, D
机构：
[1] Hop Univ Strasbourg, Dept Infect Dis, F-67094 Strasbourg, France
[2] Hop Louis Pasteur, Dept Internal Med, F-68000 Colmar, France
[3] Hop Univ Strasbourg, Vasc & Cardiac Surg Dept, F-67094 Strasbourg, France
来源：
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2005年 / 24卷 / 05期
关键词：
D O I：
10.1007/s10096-005-1327-5
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Reported here is a case of mediastinitis caused by Aspergillus fumigatus and Staphylococcus epidermidis following a heart transplantation that was successfully treated with amphotericin B in combination with new antifungal drugs (caspofungin and voriconazole), antibiotics and superficial wound drainage. A review of the literature revealed that Aspergillus as a cause of mediastinitis has been rarely described. In the few existing reports, evolution was generally fatal, especially in immunocompromised patients, despite treatment with antifungal drugs and surgery.
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页码：347 / 349
页数：3
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